Unraveling the Fanconi anemia-DNA repair connection

Larry H. Thompson

doi:10.1038/ng0905-921

Unraveling the Fanconi anemia-DNA repair connection

Larry H. Thompson

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

How the Fanconi anemia chromosome stability pathway functions to cope with interstrand crosslinks and other DNA lesions has been elusive. The identification of two new Fanconi anemia-associated proteins with helicase motifs, FANCM and BRIP1 (also called FANCJ or BACH1), implicates the FANC nuclear core complex in recognizing or processing damaged DNA and the BRIP1 helicase as acting independently of this complex.

Original language	English (US)
Pages (from-to)	921-922
Number of pages	2
Journal	Nature Genetics
Volume	37
Issue number	9
DOIs	https://doi.org/10.1038/ng0905-921
State	Published - Sep 2005
Externally published	Yes

ASJC Scopus subject areas

Genetics(clinical)
Genetics

Access to Document

10.1038/ng0905-921

Cite this

@article{e8e064e788cd4cd8afa1cb7bfade5907,

title = "Unraveling the Fanconi anemia-DNA repair connection",

abstract = "How the Fanconi anemia chromosome stability pathway functions to cope with interstrand crosslinks and other DNA lesions has been elusive. The identification of two new Fanconi anemia-associated proteins with helicase motifs, FANCM and BRIP1 (also called FANCJ or BACH1), implicates the FANC nuclear core complex in recognizing or processing damaged DNA and the BRIP1 helicase as acting independently of this complex.",

author = "Thompson, {Larry H.}",

year = "2005",

month = sep,

doi = "10.1038/ng0905-921",

language = "English (US)",

volume = "37",

pages = "921--922",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group",

number = "9",

}

TY - JOUR

T1 - Unraveling the Fanconi anemia-DNA repair connection

AU - Thompson, Larry H.

PY - 2005/9

Y1 - 2005/9

N2 - How the Fanconi anemia chromosome stability pathway functions to cope with interstrand crosslinks and other DNA lesions has been elusive. The identification of two new Fanconi anemia-associated proteins with helicase motifs, FANCM and BRIP1 (also called FANCJ or BACH1), implicates the FANC nuclear core complex in recognizing or processing damaged DNA and the BRIP1 helicase as acting independently of this complex.

AB - How the Fanconi anemia chromosome stability pathway functions to cope with interstrand crosslinks and other DNA lesions has been elusive. The identification of two new Fanconi anemia-associated proteins with helicase motifs, FANCM and BRIP1 (also called FANCJ or BACH1), implicates the FANC nuclear core complex in recognizing or processing damaged DNA and the BRIP1 helicase as acting independently of this complex.

UR - http://www.scopus.com/inward/record.url?scp=25144492769&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=25144492769&partnerID=8YFLogxK

U2 - 10.1038/ng0905-921

DO - 10.1038/ng0905-921

M3 - Article

C2 - 16132046

AN - SCOPUS:25144492769

VL - 37

SP - 921

EP - 922

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 9

ER -

Unraveling the Fanconi anemia-DNA repair connection

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this