Unraveling the Fanconi anemia-DNA repair connection

Larry H. Thompson

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

How the Fanconi anemia chromosome stability pathway functions to cope with interstrand crosslinks and other DNA lesions has been elusive. The identification of two new Fanconi anemia-associated proteins with helicase motifs, FANCM and BRIP1 (also called FANCJ or BACH1), implicates the FANC nuclear core complex in recognizing or processing damaged DNA and the BRIP1 helicase as acting independently of this complex.

Original languageEnglish (US)
Pages (from-to)921-922
Number of pages2
JournalNature Genetics
Volume37
Issue number9
DOIs
StatePublished - Sep 2005
Externally publishedYes

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

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