Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression.

Alvin Berger; David M. Mutch; J. Bruce German; Matthew Alan Roberts

Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression.

Alvin Berger, David M. Mutch, J. Bruce German, Matthew Alan Roberts

Research output: Contribution to journal › Article › peer-review

Abstract

The functions, actions, and regulation of polyunsaturated fatty acids (PUFAs) are beginning to be unraveled. Mice were fed diets rich in either arachidonic acid, docosahexaenoic acid, or both. Liver and hippocampus tissue were then analyzed through a combined gene expression-, lipid-, and behavioral- profiling strategy. Novel hippocampal PUFA-molecular targets suggest that PUFA transcriptionally regulated genes with roles in appetite and learning.

Original language	English (US)
Journal	Genome Biology
Volume	3
Issue number	7
State	Published - May 23 2002
Externally published	Yes

ASJC Scopus subject areas

Genetics

Fingerprint Dive into the research topics of 'Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression.'. Together they form a unique fingerprint.

Cite this

@article{afccaac2623c41b0bd0ef1d890ae5c37,

title = "Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression.",

abstract = "The functions, actions, and regulation of polyunsaturated fatty acids (PUFAs) are beginning to be unraveled. Mice were fed diets rich in either arachidonic acid, docosahexaenoic acid, or both. Liver and hippocampus tissue were then analyzed through a combined gene expression-, lipid-, and behavioral- profiling strategy. Novel hippocampal PUFA-molecular targets suggest that PUFA transcriptionally regulated genes with roles in appetite and learning.",

author = "Alvin Berger and Mutch, {David M.} and German, {J. Bruce} and Roberts, {Matthew Alan}",

year = "2002",

month = may,

day = "23",

language = "English (US)",

volume = "3",

journal = "Genome Biology",

issn = "1465-6914",

publisher = "BioMed Central",

number = "7",

}

TY - JOUR

T1 - Unraveling lipid metabolism with microarrays

T2 - effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression.

AU - Berger, Alvin

AU - Mutch, David M.

AU - German, J. Bruce

AU - Roberts, Matthew Alan

PY - 2002/5/23

Y1 - 2002/5/23

N2 - The functions, actions, and regulation of polyunsaturated fatty acids (PUFAs) are beginning to be unraveled. Mice were fed diets rich in either arachidonic acid, docosahexaenoic acid, or both. Liver and hippocampus tissue were then analyzed through a combined gene expression-, lipid-, and behavioral- profiling strategy. Novel hippocampal PUFA-molecular targets suggest that PUFA transcriptionally regulated genes with roles in appetite and learning.

AB - The functions, actions, and regulation of polyunsaturated fatty acids (PUFAs) are beginning to be unraveled. Mice were fed diets rich in either arachidonic acid, docosahexaenoic acid, or both. Liver and hippocampus tissue were then analyzed through a combined gene expression-, lipid-, and behavioral- profiling strategy. Novel hippocampal PUFA-molecular targets suggest that PUFA transcriptionally regulated genes with roles in appetite and learning.

UR - http://www.scopus.com/inward/record.url?scp=0037161549&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037161549&partnerID=8YFLogxK

M3 - Article

C2 - 12184799

AN - SCOPUS:0037161549

VL - 3

JO - Genome Biology

JF - Genome Biology

SN - 1465-6914

IS - 7

ER -