Unique topics and issues in rheumatology and clinical immunology

Carlo Selmi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Clinicians are facing unexpected issues in everyday practice, and these may become counterintuitive or challenging. Illustrative examples are provided by the hypersensitivity to universally used immunosuppressants such as corticosteroids or antibiotics such as beta-lactam. Secondly, additional issues are represented by the discovery of new pathogenetic mechanisms involved in rheumatoid and psoriatic arthritis or other chronic inflammatory diseases, genomic susceptibility to enigmatic diseases such as giant cell arteritis, or the shared role of specific mediators such as semaphorins. Third, the therapeutic armamentarium has dramatically changed over the past decade following the introduction of biotechnological drugs, and new mechanisms are being proposed to reduce adverse events or increase the drug effectiveness, particularly on cardiovascular comorbidities. Finally, rare diseases continue to represent difficult cases, as for Cogan's syndrome, with limited literature available for clinical recommendations. For these reason, the present issue of Clinical Reviews in Allergy and Immunology is timely and dedicated to these and other unique topics in clinical immunology and allergy. The aim of this issue is thus to help clinicians involved in internal medicine as well as allergists and clinical immunologists while discussing new pathways that will prove important in the near future.

Original languageEnglish (US)
Pages (from-to)1-5
Number of pages5
JournalClinical Reviews in Allergy and Immunology
Volume47
Issue number1
DOIs
StatePublished - 2014

Fingerprint

Rheumatology
Allergy and Immunology
Cogan Syndrome
Semaphorins
Giant Cell Arteritis
Psoriatic Arthritis
Disease Susceptibility
beta-Lactams
Immunosuppressive Agents
Internal Medicine
Rare Diseases
Pharmaceutical Preparations
Comorbidity
Rheumatoid Arthritis
Adrenal Cortex Hormones
Hypersensitivity
Chronic Disease
Anti-Bacterial Agents
Therapeutics
Allergists

Keywords

  • Antibiotics
  • Cogan syndrome
  • Cytokine
  • Hypersensitivity
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

Unique topics and issues in rheumatology and clinical immunology. / Selmi, Carlo.

In: Clinical Reviews in Allergy and Immunology, Vol. 47, No. 1, 2014, p. 1-5.

Research output: Contribution to journalArticle

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