Abstract
A 9-year-old male castrated Scottish terrier was referred to the Radiation Oncology Service at the William R. Pritchard Veterinary Medical Teaching Hospital for palliative radiation therapy of an incompletely excised, recurrent subcutaneous mast cell tumor (MCT) located over the right scapula, and surgical removal of a perianal MCT. Three weeks after initial presentation and prior to the fifth radiation treatment, the patient was presented with cloudiness of the left eye of 3-7 days duration. Ophthalmic consultation revealed 3+ aqueous flare with a dependent, swirling component filling approximately one-third of the anterior chamber. Aqueocentesis was performed under general anesthesia. Cytology revealed mast cells with highly atypical morphology and considered most consistent with neoplasia. The patient died 7 months after pathologic diagnosis of MCT on the right shoulder and 2 months after the cytologic diagnosis of malignant mast cells in the left anterior chamber. To the authors' knowledge, this is the first report of intraocular involvement in a mammal with MCTs, described here as intraocular mastocytosis.
Original language | English (US) |
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Pages (from-to) | 131-138 |
Number of pages | 8 |
Journal | Veterinary Ophthalmology |
Volume | 17 |
Issue number | 2 |
DOIs | |
State | Published - Mar 2014 |
Keywords
- Anterior chamber
- Anterior uveitis
- Intraocular
- Mast cell tumor
- Tyrosine kinase inhibitor
ASJC Scopus subject areas
- veterinary(all)