Uncovering a tumor suppressor for triple-negative breast cancers

John Albeck, Joan S. Brugge

Research output: Contribution to journalReview article

15 Citations (Scopus)

Abstract

"Triple-negative" breast cancers are aggressive malignancies that respond poorly to treatments. Now Sun et al. (2011) find that the activity of the protein tyrosine phosphatase PTPN12 is lost in a large percentage of this breast cancer subtype, offering molecular drivers and possible therapeutic targets for this heterogeneous and intractable cancer.

Original languageEnglish (US)
Pages (from-to)638-640
Number of pages3
JournalCell
Volume144
Issue number5
DOIs
StatePublished - Mar 4 2011
Externally publishedYes

Fingerprint

Triple Negative Breast Neoplasms
Protein Tyrosine Phosphatases
Sun
Tumors
Solar System
Neoplasms
Breast Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Uncovering a tumor suppressor for triple-negative breast cancers. / Albeck, John; Brugge, Joan S.

In: Cell, Vol. 144, No. 5, 04.03.2011, p. 638-640.

Research output: Contribution to journalReview article

Albeck, John ; Brugge, Joan S. / Uncovering a tumor suppressor for triple-negative breast cancers. In: Cell. 2011 ; Vol. 144, No. 5. pp. 638-640.
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