Abstract
"Triple-negative" breast cancers are aggressive malignancies that respond poorly to treatments. Now Sun et al. (2011) find that the activity of the protein tyrosine phosphatase PTPN12 is lost in a large percentage of this breast cancer subtype, offering molecular drivers and possible therapeutic targets for this heterogeneous and intractable cancer.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 638-640 |
| Number of pages | 3 |
| Journal | Cell |
| Volume | 144 |
| Issue number | 5 |
| DOIs | |
| State | Published - Mar 4 2011 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
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Cite this
Albeck, J., & Brugge, J. S. (2011). Uncovering a tumor suppressor for triple-negative breast cancers. Cell, 144(5), 638-640. https://doi.org/10.1016/j.cell.2011.02.030