Ultrasound measurement of the effect of temperature on microperfusion in the eye

Ronald H. Silverman, Roxana Ursea, Dustin Kruse, Katherine W. Ferrara, Mark J. Rondeau, D. Jackson Coleman

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Recent developments in ultrasound (US) technology have allowed the study of microperfusion in the anterior segment of the eye. Our aim was to determine the effect of the thermal environment on blood flow in the anterior segment. We measured blood flow in the major arterial circle of five rabbits. A 38-MHz US transducer was coupled to the eye with a normal saline water-bath with temperature controlled from 1°C to 38°C. The major arterial circle was localized and imaged using the swept-scan technique and M-mode data were then acquired for measurement of pulsatile flow. Peak systolic and mean velocity averaged 4.51 and 1.32 mm/s, respectively. Positive correlations were found between peak systolic (1.69%/°C) and mean (1.76%/°C) velocities and temperature. Vessel diameter (mean = 178 μm) did not show any significant change with temperature. High-resolution US flowmetry demonstrated decreasing flow rates in the iris with decreasing temperature.

Original languageEnglish (US)
Pages (from-to)1413-1419
Number of pages7
JournalUltrasound in Medicine and Biology
Volume28
Issue number11-12
DOIs
StatePublished - Nov 2002

Keywords

  • Blood flow
  • Blood velocity
  • Iris
  • Microcirculation
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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