Ultrasound-guided nerve blocks of the pelvic limb in dogs

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33 Citations (Scopus)

Abstract

Objectives: To evaluate the efficacy of ultrasound-guidance in nerve blockade of the sciatic and saphenous nerves in dogs and to determine if this technique could allow lower anaesthetic doses to be used with predictable onset and duration of effect. Study design: Prospective randomized (for dose and leg) blinded experimental crossover trial with 10 day washout period. Animals: Six healthy female Hound dogs aged 12.3 ± 0.5 (mean ± SD) months and weighing 18.7 ± 0.8 (mean ± SD) kg. Methods: An ultrasound-guided, perineural injection was used with saline at 0.2 mL kg-1 (Sal) or bupivacaine 0.5% at 0.05 (low dose; LD), 0.1 (medium dose; MD), or 0.2 (high dose; HD) mL kg-1, divided 2/3 at the sciatic nerve and 1/3 at the saphenous nerve. Blocks were performed using dexmedetomidine sedation with atipamezole reversal immediately after completion of the injections. Motor/proprioceptive and sensory functions were scored using a 0-8 and a 0-2 scale, respectively. Clinically relevant blocks were defined as a motor score ≥2 and sensory score ≥1. Nonparametric methods were used for statistical analysis. Results: No adverse effects were noted. There was a significant difference between the treatments with bupivacaine and the saline control, but not between the three bupivacaine treatments. Success rates of clinically relevant sciatic and saphenous blocks were both 67% (CI 95% 0.22-0.96). Onset and duration of the blocks were variable; 20-160 and 20-540 minutes, respectively. Conclusion and clinical relevance: None of the bupivacaine doses was significantly superior, though there was a tendency for a better block with the high bupivacaine dose. Either the technique or the doses used need further modification before this method will be useful in clinical practice.

Original languageEnglish (US)
Pages (from-to)460-470
Number of pages11
JournalVeterinary Anaesthesia and Analgesia
Volume37
Issue number5
DOIs
StatePublished - Sep 2010

Fingerprint

Nerve Block
Bupivacaine
limbs (animal)
nerve tissue
Extremities
Dogs
dogs
dosage
Sciatic Nerve
Dexmedetomidine
Injections
Cross-Over Studies
dexmedetomidine
Anesthetics
injection
Leg
hounds
methodology
duration
Prospective Studies

Keywords

  • Bupivacaine
  • Dog
  • Regional anaesthesia
  • Saphenous nerve block
  • Sciatic nerve block
  • Ultrasound guidance

ASJC Scopus subject areas

  • veterinary(all)

Cite this

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title = "Ultrasound-guided nerve blocks of the pelvic limb in dogs",
abstract = "Objectives: To evaluate the efficacy of ultrasound-guidance in nerve blockade of the sciatic and saphenous nerves in dogs and to determine if this technique could allow lower anaesthetic doses to be used with predictable onset and duration of effect. Study design: Prospective randomized (for dose and leg) blinded experimental crossover trial with 10 day washout period. Animals: Six healthy female Hound dogs aged 12.3 ± 0.5 (mean ± SD) months and weighing 18.7 ± 0.8 (mean ± SD) kg. Methods: An ultrasound-guided, perineural injection was used with saline at 0.2 mL kg-1 (Sal) or bupivacaine 0.5{\%} at 0.05 (low dose; LD), 0.1 (medium dose; MD), or 0.2 (high dose; HD) mL kg-1, divided 2/3 at the sciatic nerve and 1/3 at the saphenous nerve. Blocks were performed using dexmedetomidine sedation with atipamezole reversal immediately after completion of the injections. Motor/proprioceptive and sensory functions were scored using a 0-8 and a 0-2 scale, respectively. Clinically relevant blocks were defined as a motor score ≥2 and sensory score ≥1. Nonparametric methods were used for statistical analysis. Results: No adverse effects were noted. There was a significant difference between the treatments with bupivacaine and the saline control, but not between the three bupivacaine treatments. Success rates of clinically relevant sciatic and saphenous blocks were both 67{\%} (CI 95{\%} 0.22-0.96). Onset and duration of the blocks were variable; 20-160 and 20-540 minutes, respectively. Conclusion and clinical relevance: None of the bupivacaine doses was significantly superior, though there was a tendency for a better block with the high bupivacaine dose. Either the technique or the doses used need further modification before this method will be useful in clinical practice.",
keywords = "Bupivacaine, Dog, Regional anaesthesia, Saphenous nerve block, Sciatic nerve block, Ultrasound guidance",
author = "Yael Shilo and Pascoe, {Peter J} and Derek Cissell and Johnson, {Eric G} and Kass, {Philip H} and Wisner, {Erik R}",
year = "2010",
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language = "English (US)",
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T1 - Ultrasound-guided nerve blocks of the pelvic limb in dogs

AU - Shilo, Yael

AU - Pascoe, Peter J

AU - Cissell, Derek

AU - Johnson, Eric G

AU - Kass, Philip H

AU - Wisner, Erik R

PY - 2010/9

Y1 - 2010/9

N2 - Objectives: To evaluate the efficacy of ultrasound-guidance in nerve blockade of the sciatic and saphenous nerves in dogs and to determine if this technique could allow lower anaesthetic doses to be used with predictable onset and duration of effect. Study design: Prospective randomized (for dose and leg) blinded experimental crossover trial with 10 day washout period. Animals: Six healthy female Hound dogs aged 12.3 ± 0.5 (mean ± SD) months and weighing 18.7 ± 0.8 (mean ± SD) kg. Methods: An ultrasound-guided, perineural injection was used with saline at 0.2 mL kg-1 (Sal) or bupivacaine 0.5% at 0.05 (low dose; LD), 0.1 (medium dose; MD), or 0.2 (high dose; HD) mL kg-1, divided 2/3 at the sciatic nerve and 1/3 at the saphenous nerve. Blocks were performed using dexmedetomidine sedation with atipamezole reversal immediately after completion of the injections. Motor/proprioceptive and sensory functions were scored using a 0-8 and a 0-2 scale, respectively. Clinically relevant blocks were defined as a motor score ≥2 and sensory score ≥1. Nonparametric methods were used for statistical analysis. Results: No adverse effects were noted. There was a significant difference between the treatments with bupivacaine and the saline control, but not between the three bupivacaine treatments. Success rates of clinically relevant sciatic and saphenous blocks were both 67% (CI 95% 0.22-0.96). Onset and duration of the blocks were variable; 20-160 and 20-540 minutes, respectively. Conclusion and clinical relevance: None of the bupivacaine doses was significantly superior, though there was a tendency for a better block with the high bupivacaine dose. Either the technique or the doses used need further modification before this method will be useful in clinical practice.

AB - Objectives: To evaluate the efficacy of ultrasound-guidance in nerve blockade of the sciatic and saphenous nerves in dogs and to determine if this technique could allow lower anaesthetic doses to be used with predictable onset and duration of effect. Study design: Prospective randomized (for dose and leg) blinded experimental crossover trial with 10 day washout period. Animals: Six healthy female Hound dogs aged 12.3 ± 0.5 (mean ± SD) months and weighing 18.7 ± 0.8 (mean ± SD) kg. Methods: An ultrasound-guided, perineural injection was used with saline at 0.2 mL kg-1 (Sal) or bupivacaine 0.5% at 0.05 (low dose; LD), 0.1 (medium dose; MD), or 0.2 (high dose; HD) mL kg-1, divided 2/3 at the sciatic nerve and 1/3 at the saphenous nerve. Blocks were performed using dexmedetomidine sedation with atipamezole reversal immediately after completion of the injections. Motor/proprioceptive and sensory functions were scored using a 0-8 and a 0-2 scale, respectively. Clinically relevant blocks were defined as a motor score ≥2 and sensory score ≥1. Nonparametric methods were used for statistical analysis. Results: No adverse effects were noted. There was a significant difference between the treatments with bupivacaine and the saline control, but not between the three bupivacaine treatments. Success rates of clinically relevant sciatic and saphenous blocks were both 67% (CI 95% 0.22-0.96). Onset and duration of the blocks were variable; 20-160 and 20-540 minutes, respectively. Conclusion and clinical relevance: None of the bupivacaine doses was significantly superior, though there was a tendency for a better block with the high bupivacaine dose. Either the technique or the doses used need further modification before this method will be useful in clinical practice.

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