Ultrasound-guided methylene blue dye injection for parathyroid localization in the reoperative neck

Leah Candell, Michael Campbell, Wen T. Shen, Jessica E. Gosnell, Orlo H. Clark, Quan Yang Duh

Research output: Contribution to journalArticle

6 Scopus citations


Background: The goal of this study was to review a single institution's experience using intraoperative ultrasound-guided (ioUSG) methylene blue dye injection for the localization and removal of enlarged parathyroid glands in patients with primary hyperparathyroidism and a history of previous neck surgery. Methods: We performed a retrospective review of nine consecutive patients who underwent reoperative parathyroidectomy using ioUSG methylene blue dye injection. Results: All patients had successful resolution of their hyperparathyroidism, with at least a 50 % decrease in intraoperative parathyroid hormone level after resection. One patient had transient recurrent laryngeal nerve paresis. There were no permanent recurrent laryngeal nerve injuries or cases of permanent hypoparathyroidism. Conclusions: Blue dye injection is a safe and effective method of localizing diseased parathyroid glands in the reoperative neck.

Original languageEnglish (US)
Pages (from-to)88-91
Number of pages4
JournalWorld Journal of Surgery
Issue number1
StatePublished - Jan 2014


ASJC Scopus subject areas

  • Surgery

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