Ultrasound evaluation of fetuses of zinc-deprived monkeys (Macaca mulatta)

Mari S. Golub, Alice F Tarantal, M. Eric Gershwin, Carl L Keen, Andrew G Hendrickx, Bo Lonnerdal

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Fetal body movements were studied in three groups of gravid rhesus macaques fed different amounts of dietary zinc (100 μg Zn/g diet, control, n = 12;4 μg Zn/g diet, marginal deprivation, n = 7; 2 μg Zn/g diet, moderate deprivation, n = 11). Sonographic examinations were conducted during the third trimester in awake chair-restrained dams. Movement categories, derived from the human biophysical profile, were motor activity (trunk and limb movements), startle, and breathing movements. Moderately deprived fetuses were more active than controls on gestational day (GD) 115; maternal plasma zinc concentrations were significantly correlated with fetal activity at this time. In addition moderately deprived fetuses exhibited fewer breathing episodes on GDs 115-135. Biometrics measures indicated growth retardation in one moderately deprived fetus. These data suggest that moderate, but not marginal, dietary zinc deprivation influences fetal status as evaluated by sonography.

Original languageEnglish (US)
Pages (from-to)734-740
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume55
Issue number3
StatePublished - Mar 1992

Fingerprint

Macaca mulatta
Haplorhini
monkeys
fetus
Zinc
Fetal Movement
Fetus
zinc
Diet
breathing
Respiration
diet
Third Pregnancy Trimester
biometry
limbs (animal)
ultrasonography
growth retardation
Ultrasonography
Motor Activity
Extremities

Keywords

  • Biophysical profile
  • Fetus
  • Macaca mulatta
  • Monkeys
  • Nutrition
  • Pregnancy
  • Rhesus macaques
  • Ultrasonography
  • Zinc deprivation

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Ultrasound evaluation of fetuses of zinc-deprived monkeys (Macaca mulatta). / Golub, Mari S.; Tarantal, Alice F; Gershwin, M. Eric; Keen, Carl L; Hendrickx, Andrew G; Lonnerdal, Bo.

In: American Journal of Clinical Nutrition, Vol. 55, No. 3, 03.1992, p. 734-740.

Research output: Contribution to journalArticle

Golub, Mari S. ; Tarantal, Alice F ; Gershwin, M. Eric ; Keen, Carl L ; Hendrickx, Andrew G ; Lonnerdal, Bo. / Ultrasound evaluation of fetuses of zinc-deprived monkeys (Macaca mulatta). In: American Journal of Clinical Nutrition. 1992 ; Vol. 55, No. 3. pp. 734-740.
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