Ultrahigh-speed ultrahigh-resolution adaptive optics: Optical coherence tomography system for in-vivo small animal retinal imaging

Yifan Jian, Jing Xu, Robert Zawadzki, Marinko V. Sarunic

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Small animal models of human retinal diseases are a critical component of vision research. In this report, we present an ultrahigh-resolution ultrahigh-speed adaptive optics optical coherence tomography (AO-OCT) system for small animal retinal imaging (mouse, fish, etc.). We adapted our imaging system to different types of small animals in accordance with the optical properties of their eyes. Results of AO-OCT images of small animal retinas acquired with AO correction are presented. Cellular structures including nerve fiber bundles, capillary networks and detailed double-cone photoreceptors are visualized.

Original languageEnglish (US)
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
Volume8571
DOIs
StatePublished - May 22 2013
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII - San Francisco, CA, United States
Duration: Feb 4 2013Feb 6 2013

Other

OtherOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
CountryUnited States
CitySan Francisco, CA
Period2/4/132/6/13

Keywords

  • Adaptive Optics
  • Optical Coherence Tomography
  • Small Animal

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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    Jian, Y., Xu, J., Zawadzki, R., & Sarunic, M. V. (2013). Ultrahigh-speed ultrahigh-resolution adaptive optics: Optical coherence tomography system for in-vivo small animal retinal imaging. In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII (Vol. 8571). [85711R] https://doi.org/10.1117/12.2006652