Abstract
Ultrahighs peed Spectral/Fourier domain ophthalmic OCT imaging at 70, 000-312,500 a xial scansper second is demonstrated using a high speed CMOS camera at 800 nm. Comparative imaging results of the fovea illustrate the performance tradeoffs between different imaging speeds and spectrometer configurations. Dense 3 Dvolumetric acquisitions show minimal motion artifacts when acquired at 250,000 axial scans per second. The porous structure of the lamina cribrosa is shown in enface images extracted from a densevol umetric acquisition of the optical nerve head acquired at 106, 382 a xial scans persecond. Rapid repeated volume imaging (4D-OCT) shows blood flow in retinal capillaries. Boundaries of the capillary network are enhanced by motion contrast. 3D volumetric data acquired at 49,000 axial scans persecond using an InGaAs camera at 1050 nm is compared to volumetric data acquired at 101, 010 axial scans per second using a CMOS camera at 800nm. Averaging of adjacent cross sectional scans in the volume is shown to increase contrast in the images and reduce speckle. The enhanced penetration of the 1050 nm compared to the 800 nm OCT im aging system is shown. Dense 2D/3 D data sets and 4D-OCT repeated volume imaging pro mise altern ative methods for diagnosis and monitoring of disease.
| Original language | English (US) |
|---|---|
| Title of host publication | Optical Coherence Tomography and Coherence Techniques IV |
| Volume | 7372 |
| DOIs | |
| State | Published - Dec 1 2009 |
| Externally published | Yes |
| Event | Optical Coherence Tomography and Coherence Techniques IV - Munich, Germany Duration: Jun 14 2009 → Jun 17 2009 |
Other
| Other | Optical Coherence Tomography and Coherence Techniques IV |
|---|---|
| Country | Germany |
| City | Munich |
| Period | 6/14/09 → 6/17/09 |
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Keywords
- Biomedical imaging
- Ophthalmic imaging
- Optical coherence tomography
- Spectrometers and spectroscopic instrumentation
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging
Cite this
Ultrahigh speed Spectral / Fourier domain OCT imaging in ophthalmology. / Potsaid, Benjamin; Gorczynska, Iwona; Srinivasan, Vivek; Chen, Yueli; Liu, Jonathan; Jiang, James; Cable, Alex; Duker, Jay S.; Fujimoto, James G.
Optical Coherence Tomography and Coherence Techniques IV. Vol. 7372 2009. 73721P.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Ultrahigh speed Spectral / Fourier domain OCT imaging in ophthalmology
AU - Potsaid, Benjamin
AU - Gorczynska, Iwona
AU - Srinivasan, Vivek
AU - Chen, Yueli
AU - Liu, Jonathan
AU - Jiang, James
AU - Cable, Alex
AU - Duker, Jay S.
AU - Fujimoto, James G.
PY - 2009/12/1
Y1 - 2009/12/1
N2 - Ultrahighs peed Spectral/Fourier domain ophthalmic OCT imaging at 70, 000-312,500 a xial scansper second is demonstrated using a high speed CMOS camera at 800 nm. Comparative imaging results of the fovea illustrate the performance tradeoffs between different imaging speeds and spectrometer configurations. Dense 3 Dvolumetric acquisitions show minimal motion artifacts when acquired at 250,000 axial scans per second. The porous structure of the lamina cribrosa is shown in enface images extracted from a densevol umetric acquisition of the optical nerve head acquired at 106, 382 a xial scans persecond. Rapid repeated volume imaging (4D-OCT) shows blood flow in retinal capillaries. Boundaries of the capillary network are enhanced by motion contrast. 3D volumetric data acquired at 49,000 axial scans persecond using an InGaAs camera at 1050 nm is compared to volumetric data acquired at 101, 010 axial scans per second using a CMOS camera at 800nm. Averaging of adjacent cross sectional scans in the volume is shown to increase contrast in the images and reduce speckle. The enhanced penetration of the 1050 nm compared to the 800 nm OCT im aging system is shown. Dense 2D/3 D data sets and 4D-OCT repeated volume imaging pro mise altern ative methods for diagnosis and monitoring of disease.
AB - Ultrahighs peed Spectral/Fourier domain ophthalmic OCT imaging at 70, 000-312,500 a xial scansper second is demonstrated using a high speed CMOS camera at 800 nm. Comparative imaging results of the fovea illustrate the performance tradeoffs between different imaging speeds and spectrometer configurations. Dense 3 Dvolumetric acquisitions show minimal motion artifacts when acquired at 250,000 axial scans per second. The porous structure of the lamina cribrosa is shown in enface images extracted from a densevol umetric acquisition of the optical nerve head acquired at 106, 382 a xial scans persecond. Rapid repeated volume imaging (4D-OCT) shows blood flow in retinal capillaries. Boundaries of the capillary network are enhanced by motion contrast. 3D volumetric data acquired at 49,000 axial scans persecond using an InGaAs camera at 1050 nm is compared to volumetric data acquired at 101, 010 axial scans per second using a CMOS camera at 800nm. Averaging of adjacent cross sectional scans in the volume is shown to increase contrast in the images and reduce speckle. The enhanced penetration of the 1050 nm compared to the 800 nm OCT im aging system is shown. Dense 2D/3 D data sets and 4D-OCT repeated volume imaging pro mise altern ative methods for diagnosis and monitoring of disease.
KW - Biomedical imaging
KW - Ophthalmic imaging
KW - Optical coherence tomography
KW - Spectrometers and spectroscopic instrumentation
UR - http://www.scopus.com/inward/record.url?scp=79953048851&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953048851&partnerID=8YFLogxK
U2 - 10.1117/12.831866
DO - 10.1117/12.831866
M3 - Conference contribution
AN - SCOPUS:79953048851
SN - 9780819476487
VL - 7372
BT - Optical Coherence Tomography and Coherence Techniques IV
ER -