Abstract
Ultrafiltrate and total plasma and cerebrospinal fluid (CSF) platinum concentrations were examined in a patient with neuroblastoma following a 2-hour infusion of 120 mg/m2 of cisplatin. Total plasma platinum was 93.4% bound, while the ultrafiltrate of plasma accounted for the remaining 6.6%. The CSF ultrafiltrate resulted in equivalent concentrations of platinum to total CSF platinum. CSF concentrations were 2.9% of the total plasma platinum and 43.5% of the ultrafiltrate plasma platinum 2 hours after the end of the infusion.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1441-1442 |
| Number of pages | 2 |
| Journal | Cancer Treatment Reports |
| Volume | 69 |
| Issue number | 12 |
| State | Published - 1985 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Ultrafiltrate and total platinum in plasma and cerebrospinal fluid in a patient with neuroblastoma. / DeGregorio, M. W.; King, O. Y.; Holleran, W. M.; Wilbur, B. J.; Cadman, E. C.; Deisseroth, A. B.; Wilbur, J. R.
In: Cancer Treatment Reports, Vol. 69, No. 12, 1985, p. 1441-1442.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ultrafiltrate and total platinum in plasma and cerebrospinal fluid in a patient with neuroblastoma
AU - DeGregorio, M. W.
AU - King, O. Y.
AU - Holleran, W. M.
AU - Wilbur, B. J.
AU - Cadman, E. C.
AU - Deisseroth, A. B.
AU - Wilbur, J. R.
PY - 1985
Y1 - 1985
N2 - Ultrafiltrate and total plasma and cerebrospinal fluid (CSF) platinum concentrations were examined in a patient with neuroblastoma following a 2-hour infusion of 120 mg/m2 of cisplatin. Total plasma platinum was 93.4% bound, while the ultrafiltrate of plasma accounted for the remaining 6.6%. The CSF ultrafiltrate resulted in equivalent concentrations of platinum to total CSF platinum. CSF concentrations were 2.9% of the total plasma platinum and 43.5% of the ultrafiltrate plasma platinum 2 hours after the end of the infusion.
AB - Ultrafiltrate and total plasma and cerebrospinal fluid (CSF) platinum concentrations were examined in a patient with neuroblastoma following a 2-hour infusion of 120 mg/m2 of cisplatin. Total plasma platinum was 93.4% bound, while the ultrafiltrate of plasma accounted for the remaining 6.6%. The CSF ultrafiltrate resulted in equivalent concentrations of platinum to total CSF platinum. CSF concentrations were 2.9% of the total plasma platinum and 43.5% of the ultrafiltrate plasma platinum 2 hours after the end of the infusion.
UR - http://www.scopus.com/inward/record.url?scp=0022333547&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022333547&partnerID=8YFLogxK
M3 - Article
C2 - 4075318
AN - SCOPUS:0022333547
VL - 69
SP - 1441
EP - 1442
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
SN - 0027-8874
IS - 12
ER -