Abstract
Ultrafiltrate and total plasma and cerebrospinal fluid (CSF) platinum concentrations were examined in a patient with neuroblastoma following a 2-hour infusion of 120 mg/m2 of cisplatin. Total plasma platinum was 93.4% bound, while the ultrafiltrate of plasma accounted for the remaining 6.6%. The CSF ultrafiltrate resulted in equivalent concentrations of platinum to total CSF platinum. CSF concentrations were 2.9% of the total plasma platinum and 43.5% of the ultrafiltrate plasma platinum 2 hours after the end of the infusion.
Original language | English (US) |
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Pages (from-to) | 1441-1442 |
Number of pages | 2 |
Journal | Cancer Treatment Reports |
Volume | 69 |
Issue number | 12 |
State | Published - 1985 |
Externally published | Yes |
ASJC Scopus subject areas
- Cancer Research
- Oncology