Ultrafast parallel coherence gating for an adaptive optics retina camera

Junle Qu, Ravi Jonnal, Donald T. Miller

Research output: Contribution to journalConference article

4 Scopus citations

Abstract

We have constructed an en face coherence gated camera for optically sectioning the in vivo human retina. Coherence gating is generated by a free-space Michelson interferometer employing a superluminescent diode for illuminating the retinal tissue; voice coil and piezo-electric translators for controlling the optical path length of the reference channel; and a scientific-grade CCD camera for recording 2-D retinal interferograms. A conventional 1-D OCT is incorporated for tracking the axial motion of the retina and controlling the gating position. En face slices of test objects and retinal tissue were obtained using a four-step (λ/4) phase shift method. Ultrafast acquisition of four interferograms in less than 7 milliseconds has been achieved to mitigate eye motion blur. A 5-step reconstruction algorithm that is more robust to phase shift error and noise was compared to the 4-step. The axial width of the point spread function and the sensitivity of the camera were measured near 10μm and 76 dB, respectively, which is substantially better than current flood-illuminated and confocal scanning laser ophthalmoscopes equipped with adaptive optics.

Original languageEnglish (US)
Pages (from-to)352-359
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume4956
DOIs
StatePublished - Dec 5 2003
Externally publishedYes
EventPROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII - San Jose, CA, United States
Duration: Jan 27 2003Jan 29 2003

Keywords

  • Adaptive optics
  • Coherence gating
  • Confocal scanning laser ophthalmoscope
  • Eye
  • Michelson interferometer
  • Optical coherence tomography
  • Retina
  • Retina imaging

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

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