Abstract
Tyzzer's disease is an infectious disease caused by Clostridium piliforme. The most susceptible species are horses, rabbits, and laboratory animals. This chapter discusses etiology, epidemiology, pathogenesis, clinical signs, clinico-pathologic findings, diagnosis, treatment, prevention and control for Tyzzer's disease. A presumptive diagnosis of Tyzzer's disease can be reached based on gross observations. A definitive diagnosis, however, should be based upon the histologic demonstration of hepatic, intestinal, and/or myocardial lesions and the presence of bacteria in the cytoplasm of affected cells. As with the clinical signs and gross lesions, microscopic changes are similar in all the species. Due to the impossibility of cultivating C. piliforme in vitro using conventional cultural methods, antimicrobial susceptibility patterns were determined in embryonated eggs. Penicillin, tetracycline, erythromycin, and streptomycin were effective against this microorganism. Good hygiene may be beneficial for decreasing the likelihood that disease will occur.
| Original language | English (US) |
|---|---|
| Title of host publication | Clostridial Diseases in Animals |
| Publisher | wiley |
| Pages | 281-291 |
| Number of pages | 11 |
| ISBN (Electronic) | 9781118728291 |
| ISBN (Print) | 9781118728406 |
| DOIs | |
| State | Published - Apr 8 2016 |
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Keywords
- Adult horses
- C. piliforme
- Erythromycin
- Penicillin
- Streptomycin
- Tetracycline
- Tyzzer's disease
ASJC Scopus subject areas
- veterinary(all)
Cite this
Tyzzer's Disease. / Fresneda, Karina C.; Carvallo chaigneau, Francisco R.
Clostridial Diseases in Animals. wiley, 2016. p. 281-291.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Tyzzer's Disease
AU - Fresneda, Karina C.
AU - Carvallo chaigneau, Francisco R
PY - 2016/4/8
Y1 - 2016/4/8
N2 - Tyzzer's disease is an infectious disease caused by Clostridium piliforme. The most susceptible species are horses, rabbits, and laboratory animals. This chapter discusses etiology, epidemiology, pathogenesis, clinical signs, clinico-pathologic findings, diagnosis, treatment, prevention and control for Tyzzer's disease. A presumptive diagnosis of Tyzzer's disease can be reached based on gross observations. A definitive diagnosis, however, should be based upon the histologic demonstration of hepatic, intestinal, and/or myocardial lesions and the presence of bacteria in the cytoplasm of affected cells. As with the clinical signs and gross lesions, microscopic changes are similar in all the species. Due to the impossibility of cultivating C. piliforme in vitro using conventional cultural methods, antimicrobial susceptibility patterns were determined in embryonated eggs. Penicillin, tetracycline, erythromycin, and streptomycin were effective against this microorganism. Good hygiene may be beneficial for decreasing the likelihood that disease will occur.
AB - Tyzzer's disease is an infectious disease caused by Clostridium piliforme. The most susceptible species are horses, rabbits, and laboratory animals. This chapter discusses etiology, epidemiology, pathogenesis, clinical signs, clinico-pathologic findings, diagnosis, treatment, prevention and control for Tyzzer's disease. A presumptive diagnosis of Tyzzer's disease can be reached based on gross observations. A definitive diagnosis, however, should be based upon the histologic demonstration of hepatic, intestinal, and/or myocardial lesions and the presence of bacteria in the cytoplasm of affected cells. As with the clinical signs and gross lesions, microscopic changes are similar in all the species. Due to the impossibility of cultivating C. piliforme in vitro using conventional cultural methods, antimicrobial susceptibility patterns were determined in embryonated eggs. Penicillin, tetracycline, erythromycin, and streptomycin were effective against this microorganism. Good hygiene may be beneficial for decreasing the likelihood that disease will occur.
KW - Adult horses
KW - C. piliforme
KW - Erythromycin
KW - Penicillin
KW - Streptomycin
KW - Tetracycline
KW - Tyzzer's disease
UR - http://www.scopus.com/inward/record.url?scp=85024841869&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85024841869&partnerID=8YFLogxK
U2 - 10.1002/9781118728291.ch24
DO - 10.1002/9781118728291.ch24
M3 - Chapter
AN - SCOPUS:85024841869
SN - 9781118728406
SP - 281
EP - 291
BT - Clostridial Diseases in Animals
PB - wiley
ER -