Type D SRV-2 virus-specific CD8+ and CD4- CD8- T cells that regulate virus-induced T cell proliferation in Celebes macaques.

A. Malley, N. Pangares, S. K. Mayo, M. Zeleny-Pooley, Jose V Torres, E. Benjamin, M. K. Axthelm

Research output: Contribution to journalArticle

Abstract

These studies defined SRV-2 envelope peptides 96-102, 127-152, and 233-249 as T cell epitopes that induce significant T cell proliferation. Peripheral blood lymphocytes of Celebes macaques (Macaca nigra) exposed to SRV-2 and currently virus- antibody+, cultured with SRV-2 virus show strongly suppressed T cell responses and have two immunoregulatory T cell populations.

Original languageEnglish (US)
Pages (from-to)80-85
Number of pages6
JournalJournal of Medical Primatology
Volume22
Issue number2-3
StatePublished - Feb 1993
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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    Malley, A., Pangares, N., Mayo, S. K., Zeleny-Pooley, M., Torres, J. V., Benjamin, E., & Axthelm, M. K. (1993). Type D SRV-2 virus-specific CD8+ and CD4- CD8- T cells that regulate virus-induced T cell proliferation in Celebes macaques. Journal of Medical Primatology, 22(2-3), 80-85.