Two cortical systems for memory-guided behaviour

Charan Ranganath, Maureen Ritchey

Research output: Contribution to journalArticle

431 Citations (Scopus)

Abstract

Although the perirhinal cortex (PRC), parahippocampal cortex (PHC) and retrosplenial cortex (RSC) have an essential role in memory, the precise functions of these areas are poorly understood. Here, we review the anatomical and functional characteristics of these areas based on studies in humans, monkeys and rats. Our Review suggests that the PRC and PHC-RSC are core components of two separate large-scale cortical networks that are dissociable by neuroanatomy, susceptibility to disease and function. These networks not only support different types of memory but also appear to support different aspects of cognition.

Original languageEnglish (US)
Pages (from-to)713-726
Number of pages14
JournalNature Reviews Neuroscience
Volume13
Issue number10
DOIs
StatePublished - Oct 2012

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Neuroanatomy
Disease Susceptibility
Cognition
Haplorhini
Perirhinal Cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Two cortical systems for memory-guided behaviour. / Ranganath, Charan; Ritchey, Maureen.

In: Nature Reviews Neuroscience, Vol. 13, No. 10, 10.2012, p. 713-726.

Research output: Contribution to journalArticle

Ranganath, Charan ; Ritchey, Maureen. / Two cortical systems for memory-guided behaviour. In: Nature Reviews Neuroscience. 2012 ; Vol. 13, No. 10. pp. 713-726.
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