Two cases of Kaposi's sarcoma in renal and liver transplant recipients treated with interferon

Orsolya Halmos, Paolo Inturri, Alessandra Galligioni, Domenico Di Landro, Paolo Rigotti, Umberto Tedeschi, Agnese Graziotto, Patrizia Burra, Alessandro Poletti, Lorenzo Rossaro

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15 Scopus citations

Abstract

We report two cases of Kaposi's sarcoma in recipients of solid organ transplants, presenting (Case 1) 12 months after liver transplantation and (Case 2) 7 months after kidney transplantation. Both patients share the following features: natives from the Mediterranean area (Southern Italy), multiple immunosuppressive regimen, infection with hepatitis B and cytomegalovirus. During the 3 yr of follow-up after the diagnosis, their immunosuppressive regimen was reduced and they were treated with alpha interferon with remission of the clinical findings. The management of Kaposi's sarcoma in organ transplant recipients remains a controversial issue because of the risks of organ rejection associated with the reduction of immunosuppression and with the use of interferon.

Original languageEnglish (US)
Pages (from-to)374-378
Number of pages5
JournalClinical Transplantation
Volume10
Issue number4
StatePublished - 1996
Externally publishedYes

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Keywords

  • Hepatitis B virus
  • Immunosuppression
  • Interferon
  • Kaposi's sarcoma
  • Kidney transplantation
  • Liver transplantation

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Halmos, O., Inturri, P., Galligioni, A., Di Landro, D., Rigotti, P., Tedeschi, U., Graziotto, A., Burra, P., Poletti, A., & Rossaro, L. (1996). Two cases of Kaposi's sarcoma in renal and liver transplant recipients treated with interferon. Clinical Transplantation, 10(4), 374-378.