Two cases of digital defects in Macaca mulatta infants and a survey of the literature

L. Brignolo, R. Tarara, P. E. Peterson, Andrew G Hendrickx

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Although congenital digital defects, particularly polydactyly, have been reported frequently in humans, their occurrence in rhesus macaques is relatively rare. We observed two cases of spontaneous digital defects in male rhesus monkey infants recently born at the California Regional Primate Research Center. One infant exhibited bilateral postaxial polydactyly and the other infant had bilateral oligodactyly with unilateral phalangeal duplication. In this report, we present the clinical/pathological details of these cases as well as discuss the embryology of normal and abnormal limb development. We will also summarize a variety of spontaneous and experimentally induced digital defects that have been reported in several nonhuman primate species.

Original languageEnglish (US)
Pages (from-to)98-103
Number of pages6
JournalJournal of Medical Primatology
Issue number2
StatePublished - 2002


  • Anomalies
  • Congenital malformations
  • Ectrodactyly
  • Nonhuman primates
  • Oligodactyly
  • Polydactyly

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


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