Twenty years of acanthamoeba keratitis

F. R S Carvalho, A. S. Foronda, Mark J Mannis, A. L. Höfling-Lima, R. Belfort, Denise De Freitas

Research output: Contribution to journalArticle

44 Scopus citations


PURPOSE: We described the rate of Acanthamoeba keratitis (AK) in a referral eye center in São Paulo, Brazil, through a retrospective review of clinical and laboratorial records of patients over 2 decades. METHODS: From 1987 to 2006, a total of 581 requests for amoebic laboratory workup in cases of infectious keratitis were investigated. Statistical analyses were applied to analyze a tendency of AK cases. RESULTS: Acanthamoeba species were cultured from corneal scrapings of 185 patients, 5 of them with bilateral infection. Eighty-three percent of those patients were related with contact lens wear. CONCLUSIONS: The results suggested that patients with AK have persisted and increased over time at our ophthalmology center. Contact lenses showed to be a potential risk factor. Amoebic corneal infection can be considered as a new but well-established disease in Brazilian ophthalmology and visual sciences.

Original languageEnglish (US)
Pages (from-to)516-519
Number of pages4
Issue number5
StatePublished - Jun 2009


  • Acanthamoeba
  • Case series
  • Keratitis

ASJC Scopus subject areas

  • Ophthalmology

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    Carvalho, F. R. S., Foronda, A. S., Mannis, M. J., Höfling-Lima, A. L., Belfort, R., & Freitas, D. D. (2009). Twenty years of acanthamoeba keratitis. Cornea, 28(5), 516-519.