Tuning drug release profile from nanoporous gold thin films

Ozge Kurtulus; Erkin Seker

doi:10.1557/opl.2013.801

Tuning drug release profile from nanoporous gold thin films

Ozge Kurtulus, Erkin Seker

Electrical and Computer Engineering

Research output: Contribution to journal › Conference article › peer-review

Abstract

Nanoporous gold (np-Au) with its high surface area to volume ratio, tunable pore morphology, ease of surface modification with well-studied thiol chemistry, as well as integration with conventional microfabrication techniques is a promising candidate for controlled drug delivery studies. While it has been demonstrated that np-Au can retain and release drugs, release mechanisms and governing parameters are unclear. This paper reports on the effect of film thickness and morphology on the molecular release from np-Au films.

Original language	English (US)
Journal	Materials Research Society Symposium Proceedings
Volume	1569
DOIs	https://doi.org/10.1557/opl.2013.801
State	Published - Jan 1 2013
Event	2013 MRS Spring Meeting - San Francisco, CA, United States Duration: Apr 1 2013 → Apr 5 2013

Keywords

Au
Diffusion
Nanostructure

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1557/opl.2013.801

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abstract = "Nanoporous gold (np-Au) with its high surface area to volume ratio, tunable pore morphology, ease of surface modification with well-studied thiol chemistry, as well as integration with conventional microfabrication techniques is a promising candidate for controlled drug delivery studies. While it has been demonstrated that np-Au can retain and release drugs, release mechanisms and governing parameters are unclear. This paper reports on the effect of film thickness and morphology on the molecular release from np-Au films.",

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AB - Nanoporous gold (np-Au) with its high surface area to volume ratio, tunable pore morphology, ease of surface modification with well-studied thiol chemistry, as well as integration with conventional microfabrication techniques is a promising candidate for controlled drug delivery studies. While it has been demonstrated that np-Au can retain and release drugs, release mechanisms and governing parameters are unclear. This paper reports on the effect of film thickness and morphology on the molecular release from np-Au films.

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KW - Diffusion

KW - Nanostructure

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M3 - Conference article

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T2 - 2013 MRS Spring Meeting

Y2 - 1 April 2013 through 5 April 2013

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Tuning drug release profile from nanoporous gold thin films

Abstract

Keywords

ASJC Scopus subject areas

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