Tuning crystallization pathways through sequence engineering of biomimetic polymers

Xiang Ma, Shuai Zhang, Fang Jiao, Christina J. Newcomb, Yuliang Zhang, Arushi Prakash, Zhihao Liao, Marcel D. Baer, Christopher J. Mundy, James Pfaendtner, Aleksandr Noy, Chun Long Chen, James J. De Yoreo

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Two-step nucleation pathways in which disordered, amorphous, or dense liquid states precede the appearance of crystalline phases have been reported for a wide range of materials, but the dynamics of such pathways are poorly understood. Moreover, whether these pathways are general features of crystallizing systems or a consequence of system-specific structural details that select for direct versus two-step processes is unknown. Using atomic force microscopy to directly observe crystallization of sequence-defined polymers, we show that crystallization pathways are indeed sequence dependent. When a short hydrophobic region is added to a sequence that directly forms crystalline particles, crystallization instead follows a two-step pathway that begins with the creation of disordered clusters of 10-20 molecules and is characterized by highly non-linear crystallization kinetics in which clusters transform into ordered structures that then enter the growth phase. The results shed new light on non-classical crystallization mechanisms and have implications for the design of self-assembling polymer systems.

Original languageEnglish (US)
Pages (from-to)767-774
Number of pages8
JournalNature Materials
Volume16
Issue number7
DOIs
StatePublished - Jul 1 2017
Externally publishedYes

Fingerprint

biomimetics
Biomimetics
Crystallization
Polymers
Tuning
tuning
engineering
crystallization
polymers
Crystalline materials
Crystallization kinetics
Atomic force microscopy
assembling
Nucleation
Molecules
atomic force microscopy
nucleation
Liquids
kinetics
liquids

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Ma, X., Zhang, S., Jiao, F., Newcomb, C. J., Zhang, Y., Prakash, A., ... De Yoreo, J. J. (2017). Tuning crystallization pathways through sequence engineering of biomimetic polymers. Nature Materials, 16(7), 767-774. https://doi.org/10.1038/nmat4891

Tuning crystallization pathways through sequence engineering of biomimetic polymers. / Ma, Xiang; Zhang, Shuai; Jiao, Fang; Newcomb, Christina J.; Zhang, Yuliang; Prakash, Arushi; Liao, Zhihao; Baer, Marcel D.; Mundy, Christopher J.; Pfaendtner, James; Noy, Aleksandr; Chen, Chun Long; De Yoreo, James J.

In: Nature Materials, Vol. 16, No. 7, 01.07.2017, p. 767-774.

Research output: Contribution to journalArticle

Ma, X, Zhang, S, Jiao, F, Newcomb, CJ, Zhang, Y, Prakash, A, Liao, Z, Baer, MD, Mundy, CJ, Pfaendtner, J, Noy, A, Chen, CL & De Yoreo, JJ 2017, 'Tuning crystallization pathways through sequence engineering of biomimetic polymers', Nature Materials, vol. 16, no. 7, pp. 767-774. https://doi.org/10.1038/nmat4891
Ma X, Zhang S, Jiao F, Newcomb CJ, Zhang Y, Prakash A et al. Tuning crystallization pathways through sequence engineering of biomimetic polymers. Nature Materials. 2017 Jul 1;16(7):767-774. https://doi.org/10.1038/nmat4891
Ma, Xiang ; Zhang, Shuai ; Jiao, Fang ; Newcomb, Christina J. ; Zhang, Yuliang ; Prakash, Arushi ; Liao, Zhihao ; Baer, Marcel D. ; Mundy, Christopher J. ; Pfaendtner, James ; Noy, Aleksandr ; Chen, Chun Long ; De Yoreo, James J. / Tuning crystallization pathways through sequence engineering of biomimetic polymers. In: Nature Materials. 2017 ; Vol. 16, No. 7. pp. 767-774.
@article{3cd3d1a380764b1a82958051e5976150,
title = "Tuning crystallization pathways through sequence engineering of biomimetic polymers",
abstract = "Two-step nucleation pathways in which disordered, amorphous, or dense liquid states precede the appearance of crystalline phases have been reported for a wide range of materials, but the dynamics of such pathways are poorly understood. Moreover, whether these pathways are general features of crystallizing systems or a consequence of system-specific structural details that select for direct versus two-step processes is unknown. Using atomic force microscopy to directly observe crystallization of sequence-defined polymers, we show that crystallization pathways are indeed sequence dependent. When a short hydrophobic region is added to a sequence that directly forms crystalline particles, crystallization instead follows a two-step pathway that begins with the creation of disordered clusters of 10-20 molecules and is characterized by highly non-linear crystallization kinetics in which clusters transform into ordered structures that then enter the growth phase. The results shed new light on non-classical crystallization mechanisms and have implications for the design of self-assembling polymer systems.",
author = "Xiang Ma and Shuai Zhang and Fang Jiao and Newcomb, {Christina J.} and Yuliang Zhang and Arushi Prakash and Zhihao Liao and Baer, {Marcel D.} and Mundy, {Christopher J.} and James Pfaendtner and Aleksandr Noy and Chen, {Chun Long} and {De Yoreo}, {James J.}",
year = "2017",
month = "7",
day = "1",
doi = "10.1038/nmat4891",
language = "English (US)",
volume = "16",
pages = "767--774",
journal = "Nature Materials",
issn = "1476-1122",
publisher = "Nature Publishing Group",
number = "7",

}

TY - JOUR

T1 - Tuning crystallization pathways through sequence engineering of biomimetic polymers

AU - Ma, Xiang

AU - Zhang, Shuai

AU - Jiao, Fang

AU - Newcomb, Christina J.

AU - Zhang, Yuliang

AU - Prakash, Arushi

AU - Liao, Zhihao

AU - Baer, Marcel D.

AU - Mundy, Christopher J.

AU - Pfaendtner, James

AU - Noy, Aleksandr

AU - Chen, Chun Long

AU - De Yoreo, James J.

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Two-step nucleation pathways in which disordered, amorphous, or dense liquid states precede the appearance of crystalline phases have been reported for a wide range of materials, but the dynamics of such pathways are poorly understood. Moreover, whether these pathways are general features of crystallizing systems or a consequence of system-specific structural details that select for direct versus two-step processes is unknown. Using atomic force microscopy to directly observe crystallization of sequence-defined polymers, we show that crystallization pathways are indeed sequence dependent. When a short hydrophobic region is added to a sequence that directly forms crystalline particles, crystallization instead follows a two-step pathway that begins with the creation of disordered clusters of 10-20 molecules and is characterized by highly non-linear crystallization kinetics in which clusters transform into ordered structures that then enter the growth phase. The results shed new light on non-classical crystallization mechanisms and have implications for the design of self-assembling polymer systems.

AB - Two-step nucleation pathways in which disordered, amorphous, or dense liquid states precede the appearance of crystalline phases have been reported for a wide range of materials, but the dynamics of such pathways are poorly understood. Moreover, whether these pathways are general features of crystallizing systems or a consequence of system-specific structural details that select for direct versus two-step processes is unknown. Using atomic force microscopy to directly observe crystallization of sequence-defined polymers, we show that crystallization pathways are indeed sequence dependent. When a short hydrophobic region is added to a sequence that directly forms crystalline particles, crystallization instead follows a two-step pathway that begins with the creation of disordered clusters of 10-20 molecules and is characterized by highly non-linear crystallization kinetics in which clusters transform into ordered structures that then enter the growth phase. The results shed new light on non-classical crystallization mechanisms and have implications for the design of self-assembling polymer systems.

UR - http://www.scopus.com/inward/record.url?scp=85017512666&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85017512666&partnerID=8YFLogxK

U2 - 10.1038/nmat4891

DO - 10.1038/nmat4891

M3 - Article

C2 - 28414316

AN - SCOPUS:85017512666

VL - 16

SP - 767

EP - 774

JO - Nature Materials

JF - Nature Materials

SN - 1476-1122

IS - 7

ER -