TU‐A‐301‐03: A Multi‐Dimensional Description of Breast Anatomy Using Breast CT

S. Huang, John M Boone, K. Yang, N. Packard, S. Mckenney, N. Prionas, M. Yaffe, Karen K Lindfors

Research output: Contribution to journalArticle

Abstract

Purpose: Accurate anatomical characterization of the breast is useful in breast phantom development, computer modeling of breast imaging technologies, and computer‐aided diagnosis of various imaging tasks. Using the breast CT (bCT) data sets of women from a clinical trial, a number of two‐dimensional (2D) and three‐dimensional (3D) parameters which describe breast shape and composition are presented. Methods: The diameter, length, and volume of the pendant breast were measured for 219 bCT data sets, grouped by bra cup size. Segmented bCT data sets were used to determine the volume glandular fraction (VGF). VGF was found as a function of patient age, BIRADS density, and bra cup size. The glandular fraction was examined in coronal (GFcoronal) and sagittal (GFsagittal) planes of the breast, and the radial distribution of breast glandular fraction (RGFn) within a coronal bCT image was examined for three breast regions. The areal glandular fraction (AGF) was estimated from 2D projections of the breast (simulated by linear integration of bCT data sets) and was compared to the corresponding VGF. A 3D probability map of fibroglandular distribution was simulated using the breast metrics found in this study. Results: Breast diameter, length, and volume increase with increasing bra cup size. VGF was lower among older women and those with larger bra cup size. For each increasing BIRADS category, VGF increased by 5.62% (p < 0.001). VGF was also found to increase with AGF following a power function. Most fibroglandular tissue was distributed mainly in the central portion of the breast. Conclusions: Breast anatomy was examined and a number of parameters were described. The reported data may provide useful information for breast modeling in various imaging or dosimetry tasks.

Original languageEnglish (US)
Pages (from-to)3745
Number of pages1
JournalMedical Physics
Volume38
Issue number6
DOIs
StatePublished - 2011

Fingerprint

Anatomy
Breast

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

TU‐A‐301‐03 : A Multi‐Dimensional Description of Breast Anatomy Using Breast CT. / Huang, S.; Boone, John M; Yang, K.; Packard, N.; Mckenney, S.; Prionas, N.; Yaffe, M.; Lindfors, Karen K.

In: Medical Physics, Vol. 38, No. 6, 2011, p. 3745.

Research output: Contribution to journalArticle

Huang, S. ; Boone, John M ; Yang, K. ; Packard, N. ; Mckenney, S. ; Prionas, N. ; Yaffe, M. ; Lindfors, Karen K. / TU‐A‐301‐03 : A Multi‐Dimensional Description of Breast Anatomy Using Breast CT. In: Medical Physics. 2011 ; Vol. 38, No. 6. pp. 3745.
@article{3f2febd0782543a088fdabcc1981ce2d,
title = "TU‐A‐301‐03: A Multi‐Dimensional Description of Breast Anatomy Using Breast CT",
abstract = "Purpose: Accurate anatomical characterization of the breast is useful in breast phantom development, computer modeling of breast imaging technologies, and computer‐aided diagnosis of various imaging tasks. Using the breast CT (bCT) data sets of women from a clinical trial, a number of two‐dimensional (2D) and three‐dimensional (3D) parameters which describe breast shape and composition are presented. Methods: The diameter, length, and volume of the pendant breast were measured for 219 bCT data sets, grouped by bra cup size. Segmented bCT data sets were used to determine the volume glandular fraction (VGF). VGF was found as a function of patient age, BIRADS density, and bra cup size. The glandular fraction was examined in coronal (GFcoronal) and sagittal (GFsagittal) planes of the breast, and the radial distribution of breast glandular fraction (RGFn) within a coronal bCT image was examined for three breast regions. The areal glandular fraction (AGF) was estimated from 2D projections of the breast (simulated by linear integration of bCT data sets) and was compared to the corresponding VGF. A 3D probability map of fibroglandular distribution was simulated using the breast metrics found in this study. Results: Breast diameter, length, and volume increase with increasing bra cup size. VGF was lower among older women and those with larger bra cup size. For each increasing BIRADS category, VGF increased by 5.62{\%} (p < 0.001). VGF was also found to increase with AGF following a power function. Most fibroglandular tissue was distributed mainly in the central portion of the breast. Conclusions: Breast anatomy was examined and a number of parameters were described. The reported data may provide useful information for breast modeling in various imaging or dosimetry tasks.",
author = "S. Huang and Boone, {John M} and K. Yang and N. Packard and S. Mckenney and N. Prionas and M. Yaffe and Lindfors, {Karen K}",
year = "2011",
doi = "10.1118/1.3613093",
language = "English (US)",
volume = "38",
pages = "3745",
journal = "Medical Physics",
issn = "0094-2405",
publisher = "AAPM - American Association of Physicists in Medicine",
number = "6",

}

TY - JOUR

T1 - TU‐A‐301‐03

T2 - A Multi‐Dimensional Description of Breast Anatomy Using Breast CT

AU - Huang, S.

AU - Boone, John M

AU - Yang, K.

AU - Packard, N.

AU - Mckenney, S.

AU - Prionas, N.

AU - Yaffe, M.

AU - Lindfors, Karen K

PY - 2011

Y1 - 2011

N2 - Purpose: Accurate anatomical characterization of the breast is useful in breast phantom development, computer modeling of breast imaging technologies, and computer‐aided diagnosis of various imaging tasks. Using the breast CT (bCT) data sets of women from a clinical trial, a number of two‐dimensional (2D) and three‐dimensional (3D) parameters which describe breast shape and composition are presented. Methods: The diameter, length, and volume of the pendant breast were measured for 219 bCT data sets, grouped by bra cup size. Segmented bCT data sets were used to determine the volume glandular fraction (VGF). VGF was found as a function of patient age, BIRADS density, and bra cup size. The glandular fraction was examined in coronal (GFcoronal) and sagittal (GFsagittal) planes of the breast, and the radial distribution of breast glandular fraction (RGFn) within a coronal bCT image was examined for three breast regions. The areal glandular fraction (AGF) was estimated from 2D projections of the breast (simulated by linear integration of bCT data sets) and was compared to the corresponding VGF. A 3D probability map of fibroglandular distribution was simulated using the breast metrics found in this study. Results: Breast diameter, length, and volume increase with increasing bra cup size. VGF was lower among older women and those with larger bra cup size. For each increasing BIRADS category, VGF increased by 5.62% (p < 0.001). VGF was also found to increase with AGF following a power function. Most fibroglandular tissue was distributed mainly in the central portion of the breast. Conclusions: Breast anatomy was examined and a number of parameters were described. The reported data may provide useful information for breast modeling in various imaging or dosimetry tasks.

AB - Purpose: Accurate anatomical characterization of the breast is useful in breast phantom development, computer modeling of breast imaging technologies, and computer‐aided diagnosis of various imaging tasks. Using the breast CT (bCT) data sets of women from a clinical trial, a number of two‐dimensional (2D) and three‐dimensional (3D) parameters which describe breast shape and composition are presented. Methods: The diameter, length, and volume of the pendant breast were measured for 219 bCT data sets, grouped by bra cup size. Segmented bCT data sets were used to determine the volume glandular fraction (VGF). VGF was found as a function of patient age, BIRADS density, and bra cup size. The glandular fraction was examined in coronal (GFcoronal) and sagittal (GFsagittal) planes of the breast, and the radial distribution of breast glandular fraction (RGFn) within a coronal bCT image was examined for three breast regions. The areal glandular fraction (AGF) was estimated from 2D projections of the breast (simulated by linear integration of bCT data sets) and was compared to the corresponding VGF. A 3D probability map of fibroglandular distribution was simulated using the breast metrics found in this study. Results: Breast diameter, length, and volume increase with increasing bra cup size. VGF was lower among older women and those with larger bra cup size. For each increasing BIRADS category, VGF increased by 5.62% (p < 0.001). VGF was also found to increase with AGF following a power function. Most fibroglandular tissue was distributed mainly in the central portion of the breast. Conclusions: Breast anatomy was examined and a number of parameters were described. The reported data may provide useful information for breast modeling in various imaging or dosimetry tasks.

UR - http://www.scopus.com/inward/record.url?scp=85024786960&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85024786960&partnerID=8YFLogxK

U2 - 10.1118/1.3613093

DO - 10.1118/1.3613093

M3 - Article

AN - SCOPUS:85024786960

VL - 38

SP - 3745

JO - Medical Physics

JF - Medical Physics

SN - 0094-2405

IS - 6

ER -