T1 values of phosphomonoester and phosphocreatine of brain show no significant change during development

K. Hida; Ingrid Kwee; T. Nakada

T₁ values of phosphomonoester and phosphocreatine of brain show no significant change during development

K. Hida, Ingrid Kwee, T. Nakada

Neurology

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2 Scopus citations

Abstract

Changes in apparent ³¹P spin-lattice relaxation times (T₁) associated with brain development were investigated in rat pups. While analysis of variance showed strong age dependency in [PME]/[ATP] and [PCr]/[ATP], the T₁ values of PME, PCr, and ATP did not show any age dependency. The studies indicate that in contrast to the data which indicated aging-related changes in the T₁ values of PME, the observed changes in PME during neonatal development are likely to be quantitative in nature.

Original language	English (US)
Pages (from-to)	179-182
Number of pages	4
Journal	Magnetic Resonance in Medicine
Volume	27
Issue number	1
State	Published - 1992

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ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

Cite this

Hida, K., Kwee, I., & Nakada, T. (1992). T₁ values of phosphomonoester and phosphocreatine of brain show no significant change during development. Magnetic Resonance in Medicine, 27(1), 179-182.

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abstract = "Changes in apparent 31P spin-lattice relaxation times (T1) associated with brain development were investigated in rat pups. While analysis of variance showed strong age dependency in [PME]/[ATP] and [PCr]/[ATP], the T1 values of PME, PCr, and ATP did not show any age dependency. The studies indicate that in contrast to the data which indicated aging-related changes in the T1 values of PME, the observed changes in PME during neonatal development are likely to be quantitative in nature.",

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AB - Changes in apparent 31P spin-lattice relaxation times (T1) associated with brain development were investigated in rat pups. While analysis of variance showed strong age dependency in [PME]/[ATP] and [PCr]/[ATP], the T1 values of PME, PCr, and ATP did not show any age dependency. The studies indicate that in contrast to the data which indicated aging-related changes in the T1 values of PME, the observed changes in PME during neonatal development are likely to be quantitative in nature.

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