Tryptamine alkaloid toxicosis in feedlot sheep.

I. J. Lean, Mark L Anderson, M. G. Kerfoot, G. C. Marten

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Tryptamine alkaloid toxicosis (Phalaris staggers) was diagnosed in feedlot sheep. Clinical signs of toxicosis, which were exacerbated by excitement, included gait abnormalities, muscular tremors, nystagmus, and convulsions. An estimated 8% of the most severely affected lambs had clinical signs of toxicosis. Gross lesions detected in the brain of affected lambs consisted of focal gray-green discoloration in the brain stem and thalamus; these areas had microscopic evidence of intraneuronal pigment accumulation. Brain specimens obtained at slaughter indicated that 60% of the lambs had lesions consistent with tryptamine alkaloid toxicosis. Tryptamine alkaloids were found in low concentrations in the feed. Lambs exposed to these feeds had higher death losses than those that were not exposed to the feeds. Cobalt concentration in the feed was higher than that previously reported to be associated with Phalaris staggers.

Original languageEnglish (US)
Pages (from-to)768-771
Number of pages4
JournalJournal of the American Veterinary Medical Association
Volume195
Issue number6
StatePublished - Jan 1 1989

Fingerprint

tryptamine
Phalaris
feedlots
Alkaloids
poisoning
alkaloids
Sheep
lambs
sheep
lesions (animal)
Brain
Tremor
Cobalt
Thalamus
brain
Gait
Brain Stem
thalamus
Seizures
brain stem

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Tryptamine alkaloid toxicosis in feedlot sheep. / Lean, I. J.; Anderson, Mark L; Kerfoot, M. G.; Marten, G. C.

In: Journal of the American Veterinary Medical Association, Vol. 195, No. 6, 01.01.1989, p. 768-771.

Research output: Contribution to journalArticle

Lean, I. J. ; Anderson, Mark L ; Kerfoot, M. G. ; Marten, G. C. / Tryptamine alkaloid toxicosis in feedlot sheep. In: Journal of the American Veterinary Medical Association. 1989 ; Vol. 195, No. 6. pp. 768-771.
@article{af0708a537444ce8888353e73dcf925c,
title = "Tryptamine alkaloid toxicosis in feedlot sheep.",
abstract = "Tryptamine alkaloid toxicosis (Phalaris staggers) was diagnosed in feedlot sheep. Clinical signs of toxicosis, which were exacerbated by excitement, included gait abnormalities, muscular tremors, nystagmus, and convulsions. An estimated 8{\%} of the most severely affected lambs had clinical signs of toxicosis. Gross lesions detected in the brain of affected lambs consisted of focal gray-green discoloration in the brain stem and thalamus; these areas had microscopic evidence of intraneuronal pigment accumulation. Brain specimens obtained at slaughter indicated that 60{\%} of the lambs had lesions consistent with tryptamine alkaloid toxicosis. Tryptamine alkaloids were found in low concentrations in the feed. Lambs exposed to these feeds had higher death losses than those that were not exposed to the feeds. Cobalt concentration in the feed was higher than that previously reported to be associated with Phalaris staggers.",
author = "Lean, {I. J.} and Anderson, {Mark L} and Kerfoot, {M. G.} and Marten, {G. C.}",
year = "1989",
month = "1",
day = "1",
language = "English (US)",
volume = "195",
pages = "768--771",
journal = "Journal of the American Veterinary Medical Association",
issn = "0003-1488",
publisher = "American Veterinary Medical Association",
number = "6",

}

TY - JOUR

T1 - Tryptamine alkaloid toxicosis in feedlot sheep.

AU - Lean, I. J.

AU - Anderson, Mark L

AU - Kerfoot, M. G.

AU - Marten, G. C.

PY - 1989/1/1

Y1 - 1989/1/1

N2 - Tryptamine alkaloid toxicosis (Phalaris staggers) was diagnosed in feedlot sheep. Clinical signs of toxicosis, which were exacerbated by excitement, included gait abnormalities, muscular tremors, nystagmus, and convulsions. An estimated 8% of the most severely affected lambs had clinical signs of toxicosis. Gross lesions detected in the brain of affected lambs consisted of focal gray-green discoloration in the brain stem and thalamus; these areas had microscopic evidence of intraneuronal pigment accumulation. Brain specimens obtained at slaughter indicated that 60% of the lambs had lesions consistent with tryptamine alkaloid toxicosis. Tryptamine alkaloids were found in low concentrations in the feed. Lambs exposed to these feeds had higher death losses than those that were not exposed to the feeds. Cobalt concentration in the feed was higher than that previously reported to be associated with Phalaris staggers.

AB - Tryptamine alkaloid toxicosis (Phalaris staggers) was diagnosed in feedlot sheep. Clinical signs of toxicosis, which were exacerbated by excitement, included gait abnormalities, muscular tremors, nystagmus, and convulsions. An estimated 8% of the most severely affected lambs had clinical signs of toxicosis. Gross lesions detected in the brain of affected lambs consisted of focal gray-green discoloration in the brain stem and thalamus; these areas had microscopic evidence of intraneuronal pigment accumulation. Brain specimens obtained at slaughter indicated that 60% of the lambs had lesions consistent with tryptamine alkaloid toxicosis. Tryptamine alkaloids were found in low concentrations in the feed. Lambs exposed to these feeds had higher death losses than those that were not exposed to the feeds. Cobalt concentration in the feed was higher than that previously reported to be associated with Phalaris staggers.

UR - http://www.scopus.com/inward/record.url?scp=0024971256&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024971256&partnerID=8YFLogxK

M3 - Article

C2 - 2793545

AN - SCOPUS:0024971256

VL - 195

SP - 768

EP - 771

JO - Journal of the American Veterinary Medical Association

JF - Journal of the American Veterinary Medical Association

SN - 0003-1488

IS - 6

ER -