TRPML1ng on sparks

Research output: Contribution to journalArticlepeer-review

Abstract

In this issue of Science Signaling, Thakore et al. report that the Ca2+-permeable channel TRPML1 closely associates with ryanodine receptors to induce Ca2+ sparks in native arterial myocytes. Functional studies revealed a key role for TRPML1 channels in regulation of arterial myocyte contractility and blood pressure.

Original languageEnglish (US)
Article numbereabc0993
JournalScience Signaling
Volume13
Issue number636
DOIs
StatePublished - Jun 16 2020

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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