TRPML1ng on sparks

Madeline Nieves-Cintron; Luis F. Santana; Manuel F Navedo

doi:10.1126/scisignal.abc0993

TRPML1ng on sparks

Madeline Nieves-Cintron, Luis F. Santana, Manuel F Navedo

Research output: Contribution to journal › Review article › peer-review

Abstract

In this issue of Science Signaling, Thakore et al. report that the Ca2+-permeable channel TRPML1 closely associates with ryanodine receptors to induce Ca2+ sparks in native arterial myocytes. Functional studies revealed a key role for TRPML1 channels in regulation of arterial myocyte contractility and blood pressure.

Original language	English (US)
Journal	Science Signaling
Volume	13
Issue number	637
DOIs	https://doi.org/10.1126/scisignal.abc0993
State	Published - Jun 23 2020

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Cell Biology

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abstract = "In this issue of Science Signaling, Thakore et al. report that the Ca2+-permeable channel TRPML1 closely associates with ryanodine receptors to induce Ca2+ sparks in native arterial myocytes. Functional studies revealed a key role for TRPML1 channels in regulation of arterial myocyte contractility and blood pressure.",

author = "Madeline Nieves-Cintron and Santana, {Luis F.} and Navedo, {Manuel F}",

year = "2020",

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AU - Navedo, Manuel F

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