Abstract
In this issue of Science Signaling, Thakore et al. report that the Ca2+-permeable channel TRPML1 closely associates with ryanodine receptors to induce Ca2+ sparks in native arterial myocytes. Functional studies revealed a key role for TRPML1 channels in regulation of arterial myocyte contractility and blood pressure.
Original language | English (US) |
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Journal | Science Signaling |
Volume | 13 |
Issue number | 637 |
DOIs | |
State | Published - Jun 23 2020 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Cell Biology