TY - JOUR
T1 - Tritium AMS for biomedical applications
AU - Roberts, M. L.
AU - Velsko, C.
AU - Turteltaub, Ken W
PY - 1994/6/3
Y1 - 1994/6/3
N2 - We are developing 3H AMS to measure 3H activity of mg-sized biological samples. LLNL has already successfully applied 14C AMS to a variety of problems in the area of biomedical research. Development of 3H AMS would greatly complement these studies. The ability to perform 3H AMS measurements at sensitivities equivalent to those obtained for 14C will allow us to perform experiments using compounds that are not readily available in C-tagged form. A 3H capability would also allow us to perform unique double-labeling experiments in which we learn the fate, distribution, and metabolism of separate fractions of biological compounds.
AB - We are developing 3H AMS to measure 3H activity of mg-sized biological samples. LLNL has already successfully applied 14C AMS to a variety of problems in the area of biomedical research. Development of 3H AMS would greatly complement these studies. The ability to perform 3H AMS measurements at sensitivities equivalent to those obtained for 14C will allow us to perform experiments using compounds that are not readily available in C-tagged form. A 3H capability would also allow us to perform unique double-labeling experiments in which we learn the fate, distribution, and metabolism of separate fractions of biological compounds.
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U2 - 10.1016/0168-583X(94)96054-2
DO - 10.1016/0168-583X(94)96054-2
M3 - Article
AN - SCOPUS:0012263037
VL - 92
SP - 459
EP - 462
JO - Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
JF - Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
SN - 0168-583X
IS - 1-4
ER -