Triglyceride concentrations in neonatal foals: Serial measurement and effects of age and illness

E. H. Berryhil, K G Magdesian, Philip H Kass, J. E. Edman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Few studies have evaluated the effects of age and illness on serum triglyceride concentrations in neonatal foals. The objectives of this study were to evaluate triglyceride concentrations in neonatal foals and their dams through serial measurement immediately postpartum and at 1–2 days and 10–12 days of age, as well as to measure them in sick foals. Serially measured serum triglycerides in seven healthy foals varied with age. Median (range) triglyceride concentrations were 28 mg/dL (12–50 mg/dL), 89 mg/dL (51–264 mg/dL), and 60 mg/dL (28–135 mg/dL) immediately postpartum, at 1–2 days of age, and 10–12 days of age, respectively (P < 0.001). Triglyceride concentrations varied hourly by up to 117 mg/dL in individual foals. The dams had lower triglycerides (median, 20 mg/dL; range, 12–49 mg/dL) than the foals, once foals were >24 h old. Sick foals <24 h old had lower triglycerides than sick foals aged 1–7 days (median, 41 mg/dL [range, 16–116]; median, 110 mg/dL [range, 24–379 mg/dL]; P < 0.001). Age and triglyceride concentration showed a non-linear association independent of foal health status (P = 0.01). Sick foals with positive bacterial cultures had higher triglycerides than those with negative cultures (median, 111 mg/dL [range, 10–379 mg/dL] and median 53 mg/dL [range, 17–271 mg/dL], respectively; P = 0.033). Nonsurvivors had higher triglycerides than survivors (median, 116 mg/dL [range, 41–379 mg/dL] and median, 55 mg/dL [range, 10–311 mg/dL], respectively; P = 0.04). In conclusion, triglycerides were highest in healthy neonatal foals aged 1–2 days, and in nonsurviving sick foals and those with positive bacterial cultures. Age was associated with triglyceride concentration regardless of health status.

Original languageEnglish (US)
Pages (from-to)23-29
Number of pages7
JournalVeterinary Journal
Volume227
DOIs
StatePublished - Sep 1 2017

Fingerprint

foals
Triglycerides
triacylglycerols
health status
Postpartum Period
Health Status
Serum
Survivors

Keywords

  • Blood culture
  • Foal
  • Hyperlipidaemia
  • Lipid
  • Postpartum

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Triglyceride concentrations in neonatal foals : Serial measurement and effects of age and illness. / Berryhil, E. H.; Magdesian, K G; Kass, Philip H; Edman, J. E.

In: Veterinary Journal, Vol. 227, 01.09.2017, p. 23-29.

Research output: Contribution to journalArticle

@article{36e9a256333341eb8da34ad445f06ff8,
title = "Triglyceride concentrations in neonatal foals: Serial measurement and effects of age and illness",
abstract = "Few studies have evaluated the effects of age and illness on serum triglyceride concentrations in neonatal foals. The objectives of this study were to evaluate triglyceride concentrations in neonatal foals and their dams through serial measurement immediately postpartum and at 1–2 days and 10–12 days of age, as well as to measure them in sick foals. Serially measured serum triglycerides in seven healthy foals varied with age. Median (range) triglyceride concentrations were 28 mg/dL (12–50 mg/dL), 89 mg/dL (51–264 mg/dL), and 60 mg/dL (28–135 mg/dL) immediately postpartum, at 1–2 days of age, and 10–12 days of age, respectively (P < 0.001). Triglyceride concentrations varied hourly by up to 117 mg/dL in individual foals. The dams had lower triglycerides (median, 20 mg/dL; range, 12–49 mg/dL) than the foals, once foals were >24 h old. Sick foals <24 h old had lower triglycerides than sick foals aged 1–7 days (median, 41 mg/dL [range, 16–116]; median, 110 mg/dL [range, 24–379 mg/dL]; P < 0.001). Age and triglyceride concentration showed a non-linear association independent of foal health status (P = 0.01). Sick foals with positive bacterial cultures had higher triglycerides than those with negative cultures (median, 111 mg/dL [range, 10–379 mg/dL] and median 53 mg/dL [range, 17–271 mg/dL], respectively; P = 0.033). Nonsurvivors had higher triglycerides than survivors (median, 116 mg/dL [range, 41–379 mg/dL] and median, 55 mg/dL [range, 10–311 mg/dL], respectively; P = 0.04). In conclusion, triglycerides were highest in healthy neonatal foals aged 1–2 days, and in nonsurviving sick foals and those with positive bacterial cultures. Age was associated with triglyceride concentration regardless of health status.",
keywords = "Blood culture, Foal, Hyperlipidaemia, Lipid, Postpartum",
author = "Berryhil, {E. H.} and Magdesian, {K G} and Kass, {Philip H} and Edman, {J. E.}",
year = "2017",
month = "9",
day = "1",
doi = "10.1016/j.tvjl.2017.08.002",
language = "English (US)",
volume = "227",
pages = "23--29",
journal = "Veterinary Journal",
issn = "1090-0233",
publisher = "Bailliere Tindall Ltd",

}

TY - JOUR

T1 - Triglyceride concentrations in neonatal foals

T2 - Serial measurement and effects of age and illness

AU - Berryhil, E. H.

AU - Magdesian, K G

AU - Kass, Philip H

AU - Edman, J. E.

PY - 2017/9/1

Y1 - 2017/9/1

N2 - Few studies have evaluated the effects of age and illness on serum triglyceride concentrations in neonatal foals. The objectives of this study were to evaluate triglyceride concentrations in neonatal foals and their dams through serial measurement immediately postpartum and at 1–2 days and 10–12 days of age, as well as to measure them in sick foals. Serially measured serum triglycerides in seven healthy foals varied with age. Median (range) triglyceride concentrations were 28 mg/dL (12–50 mg/dL), 89 mg/dL (51–264 mg/dL), and 60 mg/dL (28–135 mg/dL) immediately postpartum, at 1–2 days of age, and 10–12 days of age, respectively (P < 0.001). Triglyceride concentrations varied hourly by up to 117 mg/dL in individual foals. The dams had lower triglycerides (median, 20 mg/dL; range, 12–49 mg/dL) than the foals, once foals were >24 h old. Sick foals <24 h old had lower triglycerides than sick foals aged 1–7 days (median, 41 mg/dL [range, 16–116]; median, 110 mg/dL [range, 24–379 mg/dL]; P < 0.001). Age and triglyceride concentration showed a non-linear association independent of foal health status (P = 0.01). Sick foals with positive bacterial cultures had higher triglycerides than those with negative cultures (median, 111 mg/dL [range, 10–379 mg/dL] and median 53 mg/dL [range, 17–271 mg/dL], respectively; P = 0.033). Nonsurvivors had higher triglycerides than survivors (median, 116 mg/dL [range, 41–379 mg/dL] and median, 55 mg/dL [range, 10–311 mg/dL], respectively; P = 0.04). In conclusion, triglycerides were highest in healthy neonatal foals aged 1–2 days, and in nonsurviving sick foals and those with positive bacterial cultures. Age was associated with triglyceride concentration regardless of health status.

AB - Few studies have evaluated the effects of age and illness on serum triglyceride concentrations in neonatal foals. The objectives of this study were to evaluate triglyceride concentrations in neonatal foals and their dams through serial measurement immediately postpartum and at 1–2 days and 10–12 days of age, as well as to measure them in sick foals. Serially measured serum triglycerides in seven healthy foals varied with age. Median (range) triglyceride concentrations were 28 mg/dL (12–50 mg/dL), 89 mg/dL (51–264 mg/dL), and 60 mg/dL (28–135 mg/dL) immediately postpartum, at 1–2 days of age, and 10–12 days of age, respectively (P < 0.001). Triglyceride concentrations varied hourly by up to 117 mg/dL in individual foals. The dams had lower triglycerides (median, 20 mg/dL; range, 12–49 mg/dL) than the foals, once foals were >24 h old. Sick foals <24 h old had lower triglycerides than sick foals aged 1–7 days (median, 41 mg/dL [range, 16–116]; median, 110 mg/dL [range, 24–379 mg/dL]; P < 0.001). Age and triglyceride concentration showed a non-linear association independent of foal health status (P = 0.01). Sick foals with positive bacterial cultures had higher triglycerides than those with negative cultures (median, 111 mg/dL [range, 10–379 mg/dL] and median 53 mg/dL [range, 17–271 mg/dL], respectively; P = 0.033). Nonsurvivors had higher triglycerides than survivors (median, 116 mg/dL [range, 41–379 mg/dL] and median, 55 mg/dL [range, 10–311 mg/dL], respectively; P = 0.04). In conclusion, triglycerides were highest in healthy neonatal foals aged 1–2 days, and in nonsurviving sick foals and those with positive bacterial cultures. Age was associated with triglyceride concentration regardless of health status.

KW - Blood culture

KW - Foal

KW - Hyperlipidaemia

KW - Lipid

KW - Postpartum

UR - http://www.scopus.com/inward/record.url?scp=85033221842&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85033221842&partnerID=8YFLogxK

U2 - 10.1016/j.tvjl.2017.08.002

DO - 10.1016/j.tvjl.2017.08.002

M3 - Article

C2 - 29031326

AN - SCOPUS:85033221842

VL - 227

SP - 23

EP - 29

JO - Veterinary Journal

JF - Veterinary Journal

SN - 1090-0233

ER -