Trends in the practice of radiotherapy for localized prostate cancer in Japan: A preliminary patterns of care study report

Katsumasa Nakamura, Kazuhiko Ogawa, Tokihiro Yamamoto, Tomonari Sasaki, Masahiko Koizumi, Teruki Teshima, Toshihiko Inoue

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background: This is the first study to examine the characteristics and changes of the patterns of radiotherapy for prostate cancer in Japan. Methods: The Japanese Patterns of Care Study (PCS) conducted a random survey of 84 institutions nationwide. Detailed information was collected on prostate cancer patients without distant metastases, who received radiotherapy during 1996-1998 and 1999-2001. Results: The patients were divided into three groups: The Fresh Group (n = 338) was treated with radical radiotherapy with photon beams; the Surgery Group (n = 115) was treated after prostatectomy; and the Hormone-Refractory Group (n = 117) was treated after progression from hormonal therapy. In the Fresh Group, there was a decline in the fraction of patients with T3-4 tumors, from 65.2% in 1996-1998 to 43.9% in 1999-2001. In 1999-2001, a higher median dose of 69 Gy was irradiated as compared to 65 Gy in 1996-1998. In particular, the fraction of the patients treated with doses ≥70 Gy increased from 16.4% to 46.3%. In the Surgery Group, the percentage of clinical T3-4 tumors before prostatectomy decreased from 71.4% in 1996-1998 to 16.2% in 1999-2001. The median radiation dose of 60 Gy did not change, but the 1999-2001 results showed a decrease in the use of doses <60 Gy. In the Hormone-Refractory Group, the median dose increased from 60 Gy in 1996-1998 to 67 Gy in 1999-2001. Conclusion: These data suggest that radiation doses for prostate cancer in Japan have increased dramatically within a short period of time.

Original languageEnglish (US)
Pages (from-to)527-532
Number of pages6
JournalJapanese Journal of Clinical Oncology
Volume33
Issue number10
DOIs
StatePublished - Oct 1 2003
Externally publishedYes

Fingerprint

Prostatic Neoplasms
Japan
Radiotherapy
Prostatectomy
Hormones
Radiation
Photons
Neoplasms
Neoplasm Metastasis
Therapeutics

Keywords

  • Patterns of Care Study
  • Prostate cancer
  • Radiotherapy

ASJC Scopus subject areas

  • Oncology

Cite this

Trends in the practice of radiotherapy for localized prostate cancer in Japan : A preliminary patterns of care study report. / Nakamura, Katsumasa; Ogawa, Kazuhiko; Yamamoto, Tokihiro; Sasaki, Tomonari; Koizumi, Masahiko; Teshima, Teruki; Inoue, Toshihiko.

In: Japanese Journal of Clinical Oncology, Vol. 33, No. 10, 01.10.2003, p. 527-532.

Research output: Contribution to journalArticle

Nakamura, Katsumasa ; Ogawa, Kazuhiko ; Yamamoto, Tokihiro ; Sasaki, Tomonari ; Koizumi, Masahiko ; Teshima, Teruki ; Inoue, Toshihiko. / Trends in the practice of radiotherapy for localized prostate cancer in Japan : A preliminary patterns of care study report. In: Japanese Journal of Clinical Oncology. 2003 ; Vol. 33, No. 10. pp. 527-532.
@article{2f987714e1844d1d99edaf506ad2b61d,
title = "Trends in the practice of radiotherapy for localized prostate cancer in Japan: A preliminary patterns of care study report",
abstract = "Background: This is the first study to examine the characteristics and changes of the patterns of radiotherapy for prostate cancer in Japan. Methods: The Japanese Patterns of Care Study (PCS) conducted a random survey of 84 institutions nationwide. Detailed information was collected on prostate cancer patients without distant metastases, who received radiotherapy during 1996-1998 and 1999-2001. Results: The patients were divided into three groups: The Fresh Group (n = 338) was treated with radical radiotherapy with photon beams; the Surgery Group (n = 115) was treated after prostatectomy; and the Hormone-Refractory Group (n = 117) was treated after progression from hormonal therapy. In the Fresh Group, there was a decline in the fraction of patients with T3-4 tumors, from 65.2{\%} in 1996-1998 to 43.9{\%} in 1999-2001. In 1999-2001, a higher median dose of 69 Gy was irradiated as compared to 65 Gy in 1996-1998. In particular, the fraction of the patients treated with doses ≥70 Gy increased from 16.4{\%} to 46.3{\%}. In the Surgery Group, the percentage of clinical T3-4 tumors before prostatectomy decreased from 71.4{\%} in 1996-1998 to 16.2{\%} in 1999-2001. The median radiation dose of 60 Gy did not change, but the 1999-2001 results showed a decrease in the use of doses <60 Gy. In the Hormone-Refractory Group, the median dose increased from 60 Gy in 1996-1998 to 67 Gy in 1999-2001. Conclusion: These data suggest that radiation doses for prostate cancer in Japan have increased dramatically within a short period of time.",
keywords = "Patterns of Care Study, Prostate cancer, Radiotherapy",
author = "Katsumasa Nakamura and Kazuhiko Ogawa and Tokihiro Yamamoto and Tomonari Sasaki and Masahiko Koizumi and Teruki Teshima and Toshihiko Inoue",
year = "2003",
month = "10",
day = "1",
doi = "10.1093/jjco/hyg099",
language = "English (US)",
volume = "33",
pages = "527--532",
journal = "Japanese Journal of Clinical Oncology",
issn = "0368-2811",
publisher = "Oxford University Press",
number = "10",

}

TY - JOUR

T1 - Trends in the practice of radiotherapy for localized prostate cancer in Japan

T2 - A preliminary patterns of care study report

AU - Nakamura, Katsumasa

AU - Ogawa, Kazuhiko

AU - Yamamoto, Tokihiro

AU - Sasaki, Tomonari

AU - Koizumi, Masahiko

AU - Teshima, Teruki

AU - Inoue, Toshihiko

PY - 2003/10/1

Y1 - 2003/10/1

N2 - Background: This is the first study to examine the characteristics and changes of the patterns of radiotherapy for prostate cancer in Japan. Methods: The Japanese Patterns of Care Study (PCS) conducted a random survey of 84 institutions nationwide. Detailed information was collected on prostate cancer patients without distant metastases, who received radiotherapy during 1996-1998 and 1999-2001. Results: The patients were divided into three groups: The Fresh Group (n = 338) was treated with radical radiotherapy with photon beams; the Surgery Group (n = 115) was treated after prostatectomy; and the Hormone-Refractory Group (n = 117) was treated after progression from hormonal therapy. In the Fresh Group, there was a decline in the fraction of patients with T3-4 tumors, from 65.2% in 1996-1998 to 43.9% in 1999-2001. In 1999-2001, a higher median dose of 69 Gy was irradiated as compared to 65 Gy in 1996-1998. In particular, the fraction of the patients treated with doses ≥70 Gy increased from 16.4% to 46.3%. In the Surgery Group, the percentage of clinical T3-4 tumors before prostatectomy decreased from 71.4% in 1996-1998 to 16.2% in 1999-2001. The median radiation dose of 60 Gy did not change, but the 1999-2001 results showed a decrease in the use of doses <60 Gy. In the Hormone-Refractory Group, the median dose increased from 60 Gy in 1996-1998 to 67 Gy in 1999-2001. Conclusion: These data suggest that radiation doses for prostate cancer in Japan have increased dramatically within a short period of time.

AB - Background: This is the first study to examine the characteristics and changes of the patterns of radiotherapy for prostate cancer in Japan. Methods: The Japanese Patterns of Care Study (PCS) conducted a random survey of 84 institutions nationwide. Detailed information was collected on prostate cancer patients without distant metastases, who received radiotherapy during 1996-1998 and 1999-2001. Results: The patients were divided into three groups: The Fresh Group (n = 338) was treated with radical radiotherapy with photon beams; the Surgery Group (n = 115) was treated after prostatectomy; and the Hormone-Refractory Group (n = 117) was treated after progression from hormonal therapy. In the Fresh Group, there was a decline in the fraction of patients with T3-4 tumors, from 65.2% in 1996-1998 to 43.9% in 1999-2001. In 1999-2001, a higher median dose of 69 Gy was irradiated as compared to 65 Gy in 1996-1998. In particular, the fraction of the patients treated with doses ≥70 Gy increased from 16.4% to 46.3%. In the Surgery Group, the percentage of clinical T3-4 tumors before prostatectomy decreased from 71.4% in 1996-1998 to 16.2% in 1999-2001. The median radiation dose of 60 Gy did not change, but the 1999-2001 results showed a decrease in the use of doses <60 Gy. In the Hormone-Refractory Group, the median dose increased from 60 Gy in 1996-1998 to 67 Gy in 1999-2001. Conclusion: These data suggest that radiation doses for prostate cancer in Japan have increased dramatically within a short period of time.

KW - Patterns of Care Study

KW - Prostate cancer

KW - Radiotherapy

UR - http://www.scopus.com/inward/record.url?scp=0642372936&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0642372936&partnerID=8YFLogxK

U2 - 10.1093/jjco/hyg099

DO - 10.1093/jjco/hyg099

M3 - Article

C2 - 14623922

AN - SCOPUS:0642372936

VL - 33

SP - 527

EP - 532

JO - Japanese Journal of Clinical Oncology

JF - Japanese Journal of Clinical Oncology

SN - 0368-2811

IS - 10

ER -