Abstract
Patients with myeloid blastic crisis of chronic myelogenous leukemia were treated by chemotherapy or by autologous hematopoietic reconstitution after aggressive chemotherapy. Chemotherapy alone failed to produce a second chronic phase. Autologous transplantation resulted in the establishment of a second chronic phase in two of ten patients treated with a four-drug regimen, while treatment with high-dose cytarabine with or without busulfan resulted in the establishment of a second chronic phase in three of six patients and the return of normal hematopoiesis in a fourth. Consolidation chemotherapy appeared to be beneficial.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1351-1355 |
| Number of pages | 5 |
| Journal | Cancer Treatment Reports |
| Volume | 68 |
| Issue number | 11 |
| State | Published - 1984 |
| Externally published | Yes |
ASJC Scopus subject areas
- Cancer Research
- Oncology
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Cite this
Preisler, H. D., Raza, A., Higby, D., Kirshner, J., Woll, J., Bennett, J., Winton, L., Weiner, R., Richman, C. M., & Golomb, H. (1984). Treatment of myeloid blastic crisis of chronic myelogenous leukemia. Cancer Treatment Reports, 68(11), 1351-1355.