Abstract
Patients with myeloid blastic crisis of chronic myelogenous leukemia were treated by chemotherapy or by autologous hematopoietic reconstitution after aggressive chemotherapy. Chemotherapy alone failed to produce a second chronic phase. Autologous transplantation resulted in the establishment of a second chronic phase in two of ten patients treated with a four-drug regimen, while treatment with high-dose cytarabine with or without busulfan resulted in the establishment of a second chronic phase in three of six patients and the return of normal hematopoiesis in a fourth. Consolidation chemotherapy appeared to be beneficial.
Original language | English (US) |
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Pages (from-to) | 1351-1355 |
Number of pages | 5 |
Journal | Cancer Treatment Reports |
Volume | 68 |
Issue number | 11 |
State | Published - 1984 |
Externally published | Yes |
ASJC Scopus subject areas
- Cancer Research
- Oncology