Abstract
Purpose: To report successful combined percutaneous mechanical thrombectomy and pharmacological lysis for axillosubclavian vein thrombosis, with rapid clot removal at a single setting using low-dose thrombolysis. Case Reports: Two consecutive patients presented with arm swelling; the diagnosis of axillosubclavian vein thrombosis was confirmed with duplex ultrasound. Both patients were treated percutaneously with the Solera mechanical thrombectomy device, after which 5 mg of tissue plasminogen activator were delivered within ∼10 minutes via the Trellis infusion catheter to remove any residual thrombus. Completion venography and serial duplex ultrasound scans in follow-up demonstrated widely patent axillosubclavian veins with no residual thrombus in both cases. Conclusions: Standard treatment of axillosubclavian vein thrombosis may require 12 to 36 hours, with multiple trips to the angiography suite. The novel technique combining mechanical thrombectomy and pharmacological lysis can be performed safely and successfully at a single setting with a small dose of the lytic drug.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 733-738 |
| Number of pages | 6 |
| Journal | Journal of Endovascular Therapy |
| Volume | 10 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2003 |
| Externally published | Yes |
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Keywords
- Axillosubclavian vein
- Mechanical thrombectomy
- Solera Bacchus Thrombectomy Catheter
- Thrombolysis
- Tissue plasminogen activator
- Trellis Infusion System
- Upper extremity vein thrombosis
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Treatment of Axillosubclavian Vein Thrombosis : A Novel Technique for Rapid Removal of Clot Using Low-Dose Thrombolysis. / Arko, Frank R.; Cipriano, Paul; Lee, Eugene S; Filis, Konstantinos A.; Zarins, Christopher K.; Fogarty, Thomas J.
In: Journal of Endovascular Therapy, Vol. 10, No. 4, 08.2003, p. 733-738.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Treatment of Axillosubclavian Vein Thrombosis
T2 - A Novel Technique for Rapid Removal of Clot Using Low-Dose Thrombolysis
AU - Arko, Frank R.
AU - Cipriano, Paul
AU - Lee, Eugene S
AU - Filis, Konstantinos A.
AU - Zarins, Christopher K.
AU - Fogarty, Thomas J.
PY - 2003/8
Y1 - 2003/8
N2 - Purpose: To report successful combined percutaneous mechanical thrombectomy and pharmacological lysis for axillosubclavian vein thrombosis, with rapid clot removal at a single setting using low-dose thrombolysis. Case Reports: Two consecutive patients presented with arm swelling; the diagnosis of axillosubclavian vein thrombosis was confirmed with duplex ultrasound. Both patients were treated percutaneously with the Solera mechanical thrombectomy device, after which 5 mg of tissue plasminogen activator were delivered within ∼10 minutes via the Trellis infusion catheter to remove any residual thrombus. Completion venography and serial duplex ultrasound scans in follow-up demonstrated widely patent axillosubclavian veins with no residual thrombus in both cases. Conclusions: Standard treatment of axillosubclavian vein thrombosis may require 12 to 36 hours, with multiple trips to the angiography suite. The novel technique combining mechanical thrombectomy and pharmacological lysis can be performed safely and successfully at a single setting with a small dose of the lytic drug.
AB - Purpose: To report successful combined percutaneous mechanical thrombectomy and pharmacological lysis for axillosubclavian vein thrombosis, with rapid clot removal at a single setting using low-dose thrombolysis. Case Reports: Two consecutive patients presented with arm swelling; the diagnosis of axillosubclavian vein thrombosis was confirmed with duplex ultrasound. Both patients were treated percutaneously with the Solera mechanical thrombectomy device, after which 5 mg of tissue plasminogen activator were delivered within ∼10 minutes via the Trellis infusion catheter to remove any residual thrombus. Completion venography and serial duplex ultrasound scans in follow-up demonstrated widely patent axillosubclavian veins with no residual thrombus in both cases. Conclusions: Standard treatment of axillosubclavian vein thrombosis may require 12 to 36 hours, with multiple trips to the angiography suite. The novel technique combining mechanical thrombectomy and pharmacological lysis can be performed safely and successfully at a single setting with a small dose of the lytic drug.
KW - Axillosubclavian vein
KW - Mechanical thrombectomy
KW - Solera Bacchus Thrombectomy Catheter
KW - Thrombolysis
KW - Tissue plasminogen activator
KW - Trellis Infusion System
KW - Upper extremity vein thrombosis
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UR - http://www.scopus.com/inward/citedby.url?scp=0242331805&partnerID=8YFLogxK
U2 - 10.1583/1545-1550(2003)010<0733:TOAVTA>2.0.CO;2
DO - 10.1583/1545-1550(2003)010<0733:TOAVTA>2.0.CO;2
M3 - Article
C2 - 14533970
AN - SCOPUS:0242331805
VL - 10
SP - 733
EP - 738
JO - Journal of Endovascular Therapy
JF - Journal of Endovascular Therapy
SN - 1526-6028
IS - 4
ER -