Treatment of ascites. Part III: Reinfusion and transjugular intrahepatic portosystemic shunt

Paolo Inturri, Orsolya Halmos, Lorenzo Rossaro

Research output: Contribution to journalArticlepeer-review


Many therapeutic approaches are available for the treatment of refractory ascites. The armamentarium ranges from repetitive paracentesis to the definitive cure with liver transplantation. When transplant is not an option, portocaval or peritoneovenous shunts are considered, although morbidity and mortality are significant. Reinfusion of concentrated ascites is a fascinating option but its availability is limited. Transjugular intrahepatic portosystemic shunt (TIPS) has been under evaluation in randomized controlled trials and appears promising. The choice of treatment should be determined on the basis of important factors such as prognosis (i.e., Child-Pugh score), a history of other complications related to the liver disease (i.e., variceal bleeding, hepatic encephalopathy) and the complications secondary to the presence of ascites (i.e., hepatorenal syndrome, spontaneous bacterial peritonitis, complicated umbilical hernia, hydrothorax).

Original languageEnglish (US)
Pages (from-to)571-578
Number of pages8
JournalDrugs of Today
Issue number8
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology (medical)
  • Pharmacology


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