Transposon Tn10 provides a promoter for transcription of adjacent sequences

M. S. Ciampi, M. B. Schmid, J. R. Roth

Research output: Contribution to journalArticle

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Abstract

Promoters located within the Tn10 insertion element cause transcription of 'host' sequences adjacent to both ends of the inserted Tn10 element. These promoters are usually not observed in genetic experiments because their transcripts are efficiently terminated at nearby ρ-dependent termination sites. The observations presented here provide an explanation for several confusing aspects of transposon behavior and suggest the possibility that many transposons possess promoters that have escaped detection for similar reasons.

Original languageEnglish (US)
Pages (from-to)5016-5020
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume79
Issue number16 I
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • General
  • Genetics

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