Translational cancer vaccine: From mouse to human to cat

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Acanthomatous ameloblastoma is a locally invasive tumor arising in the gingiva that can progress rapidly, invade and destroy bone. If the lesion involves the upper jaw, surgical excision may not be possible and while local control is imperative, other therapies have not been fully evaluated. The primary author's personal cat, Gabriella, developed this tumor, with gingival masses around teeth in the upper jaw and evidence of widespread bony destruction of the hard palate. Because of his involvement with Immunophotonics Inc. as an advisor, the author was aware of an in situ autologous cancer vaccine (inCVAX) that is currently under development by the company. One session was performed in a veterinary clinic in Arkansas, and two follow-up sessions at the small animal hospital at the UC Davis veterinary school. No other therapy was provided. As of this writing, 3+ years after first treatment and 3 years, 4 months after presentation, Gabriella is well, with no evidence of disease.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume9324
ISBN (Print)9781628414141
DOIs
StatePublished - 2015
EventBiophotonics and Immune Responses X - San Francisco, United States
Duration: Feb 9 2015Feb 10 2015

Other

OtherBiophotonics and Immune Responses X
CountryUnited States
CitySan Francisco
Period2/9/152/10/15

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Levenson, R. M. (2015). Translational cancer vaccine: From mouse to human to cat. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 9324). [93240C-1] SPIE. https://doi.org/10.1117/12.2079538