Abstract
The potential of autofluorescence microscopy under ultraviolet excitation is investigated as a method to visualize superficial epithelial microstructures and their modification with progression of disease. This method does not require the use of contrast agents, sectioning methods, or tissue preparation. Imaging of esophagus tissue is the focus of this study and deals with three main issues: a) What is the origin of the signal; b) How the gradual microstructure modification associated with various stages of esophageal disease is visualized; c) What are the designing parameters for in vivo implementation.
Original language | English (US) |
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Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
Volume | 7895 |
DOIs | |
State | Published - 2011 |
Event | Optical Biopsy IX - San Francisco, CA, United States Duration: Jan 24 2011 → Jan 26 2011 |
Other
Other | Optical Biopsy IX |
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Country | United States |
City | San Francisco, CA |
Period | 1/24/11 → 1/26/11 |
Keywords
- autofluorescence
- Endoscopy
- gastrointestinal
- microscopy
- real-time diagnostic imaging
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging