Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy

Bevin Lin, Shiro Urayama, Ramez M G Saroufeem, Dennis L Matthews, Stavros G. Demos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The potential of autofluorescence microscopy under ultraviolet excitation is investigated as a method to visualize superficial epithelial microstructures and their modification with progression of disease. This method does not require the use of contrast agents, sectioning methods, or tissue preparation. Imaging of esophagus tissue is the focus of this study and deals with three main issues: a) What is the origin of the signal; b) How the gradual microstructure modification associated with various stages of esophageal disease is visualized; c) What are the designing parameters for in vivo implementation.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7895
DOIs
StatePublished - 2011
EventOptical Biopsy IX - San Francisco, CA, United States
Duration: Jan 24 2011Jan 26 2011

Other

OtherOptical Biopsy IX
CountryUnited States
CitySan Francisco, CA
Period1/24/111/26/11

Fingerprint

Ultraviolet Microscopy
ultraviolet microscopy
translating
Microscopic examination
Tissue
esophagus
microstructure
Microstructure
progressions
Esophageal Diseases
Contrast Media
microscopy
Imaging techniques
preparation
Esophagus
Disease Progression
excitation

Keywords

  • autofluorescence
  • Endoscopy
  • gastrointestinal
  • microscopy
  • real-time diagnostic imaging

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Lin, B., Urayama, S., Saroufeem, R. M. G., Matthews, D. L., & Demos, S. G. (2011). Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7895). [789502] https://doi.org/10.1117/12.871718

Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy. / Lin, Bevin; Urayama, Shiro; Saroufeem, Ramez M G; Matthews, Dennis L; Demos, Stavros G.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7895 2011. 789502.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lin, B, Urayama, S, Saroufeem, RMG, Matthews, DL & Demos, SG 2011, Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7895, 789502, Optical Biopsy IX, San Francisco, CA, United States, 1/24/11. https://doi.org/10.1117/12.871718
Lin B, Urayama S, Saroufeem RMG, Matthews DL, Demos SG. Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7895. 2011. 789502 https://doi.org/10.1117/12.871718
Lin, Bevin ; Urayama, Shiro ; Saroufeem, Ramez M G ; Matthews, Dennis L ; Demos, Stavros G. / Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7895 2011.
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