Abstract
The potential of autofluorescence microscopy under ultraviolet excitation is investigated as a method to visualize superficial epithelial microstructures and their modification with progression of disease. This method does not require the use of contrast agents, sectioning methods, or tissue preparation. Imaging of esophagus tissue is the focus of this study and deals with three main issues: a) What is the origin of the signal; b) How the gradual microstructure modification associated with various stages of esophageal disease is visualized; c) What are the designing parameters for in vivo implementation.
| Original language | English (US) |
|---|---|
| Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
| Volume | 7895 |
| DOIs | |
| State | Published - 2011 |
| Event | Optical Biopsy IX - San Francisco, CA, United States Duration: Jan 24 2011 → Jan 26 2011 |
Other
| Other | Optical Biopsy IX |
|---|---|
| Country | United States |
| City | San Francisco, CA |
| Period | 1/24/11 → 1/26/11 |
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Keywords
- autofluorescence
- Endoscopy
- gastrointestinal
- microscopy
- real-time diagnostic imaging
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging
Cite this
Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy. / Lin, Bevin; Urayama, Shiro; Saroufeem, Ramez M G; Matthews, Dennis L; Demos, Stavros G.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7895 2011. 789502.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy
AU - Lin, Bevin
AU - Urayama, Shiro
AU - Saroufeem, Ramez M G
AU - Matthews, Dennis L
AU - Demos, Stavros G.
PY - 2011
Y1 - 2011
N2 - The potential of autofluorescence microscopy under ultraviolet excitation is investigated as a method to visualize superficial epithelial microstructures and their modification with progression of disease. This method does not require the use of contrast agents, sectioning methods, or tissue preparation. Imaging of esophagus tissue is the focus of this study and deals with three main issues: a) What is the origin of the signal; b) How the gradual microstructure modification associated with various stages of esophageal disease is visualized; c) What are the designing parameters for in vivo implementation.
AB - The potential of autofluorescence microscopy under ultraviolet excitation is investigated as a method to visualize superficial epithelial microstructures and their modification with progression of disease. This method does not require the use of contrast agents, sectioning methods, or tissue preparation. Imaging of esophagus tissue is the focus of this study and deals with three main issues: a) What is the origin of the signal; b) How the gradual microstructure modification associated with various stages of esophageal disease is visualized; c) What are the designing parameters for in vivo implementation.
KW - autofluorescence
KW - Endoscopy
KW - gastrointestinal
KW - microscopy
KW - real-time diagnostic imaging
UR - http://www.scopus.com/inward/record.url?scp=79954520817&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79954520817&partnerID=8YFLogxK
U2 - 10.1117/12.871718
DO - 10.1117/12.871718
M3 - Conference contribution
AN - SCOPUS:79954520817
SN - 9780819484321
VL - 7895
BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
ER -