Abstract
We present evidence of transmission of lymphadenopathy-associated virus (LAV)/human T-lymphotropic virus type III (HTLV-III) from a man to his wife, and a return to a normal number of T-helper lymphocytes and loss of antibody after discontinuing sexual exposure to LAV/HTLV-III. The man had hemophilia A, and developed the lymphadenopathy syndrome, antibody to LAV, and a low number of T-helper lymphocytes. His wife, who had no risks for the acquired immunodeficiency syndrome other than sexual contact with him, developed LAV antibody (titer, 1:160) and a mildly decreased number of T-helper cells. The husband subsequently developed the syndrome and lost the LAV antibody. During 10 months of follow-up his wife remained clinically well, discontinued exposure to semen, and then lost the LAV antibody, and regained a normal number of T-helper cells.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 545-547 |
| Number of pages | 3 |
| Journal | Annals of Internal Medicine |
| Volume | 103 |
| Issue number | 4 |
| State | Published - Oct 1985 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Medicine(all)
Cite this
Transient antibody to lymphadenopathy-associated virus/human T-lymphotropic virus type III and T-lymphocyte abnormalities in the wife of a man who developed the acquired immunodeficiency syndrome. / Burger, Harold; Weiser, Barbara; Robinson, W. S.; Lifson, J.; Engleman, E.; Rouzioux, C.; Brun-Vézinet, F.; Barré-Sinoussi, F.; Montagnier, L.; Chermann, J. C.
In: Annals of Internal Medicine, Vol. 103, No. 4, 10.1985, p. 545-547.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Transient antibody to lymphadenopathy-associated virus/human T-lymphotropic virus type III and T-lymphocyte abnormalities in the wife of a man who developed the acquired immunodeficiency syndrome.
AU - Burger, Harold
AU - Weiser, Barbara
AU - Robinson, W. S.
AU - Lifson, J.
AU - Engleman, E.
AU - Rouzioux, C.
AU - Brun-Vézinet, F.
AU - Barré-Sinoussi, F.
AU - Montagnier, L.
AU - Chermann, J. C.
PY - 1985/10
Y1 - 1985/10
N2 - We present evidence of transmission of lymphadenopathy-associated virus (LAV)/human T-lymphotropic virus type III (HTLV-III) from a man to his wife, and a return to a normal number of T-helper lymphocytes and loss of antibody after discontinuing sexual exposure to LAV/HTLV-III. The man had hemophilia A, and developed the lymphadenopathy syndrome, antibody to LAV, and a low number of T-helper lymphocytes. His wife, who had no risks for the acquired immunodeficiency syndrome other than sexual contact with him, developed LAV antibody (titer, 1:160) and a mildly decreased number of T-helper cells. The husband subsequently developed the syndrome and lost the LAV antibody. During 10 months of follow-up his wife remained clinically well, discontinued exposure to semen, and then lost the LAV antibody, and regained a normal number of T-helper cells.
AB - We present evidence of transmission of lymphadenopathy-associated virus (LAV)/human T-lymphotropic virus type III (HTLV-III) from a man to his wife, and a return to a normal number of T-helper lymphocytes and loss of antibody after discontinuing sexual exposure to LAV/HTLV-III. The man had hemophilia A, and developed the lymphadenopathy syndrome, antibody to LAV, and a low number of T-helper lymphocytes. His wife, who had no risks for the acquired immunodeficiency syndrome other than sexual contact with him, developed LAV antibody (titer, 1:160) and a mildly decreased number of T-helper cells. The husband subsequently developed the syndrome and lost the LAV antibody. During 10 months of follow-up his wife remained clinically well, discontinued exposure to semen, and then lost the LAV antibody, and regained a normal number of T-helper cells.
UR - http://www.scopus.com/inward/record.url?scp=0022137920&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022137920&partnerID=8YFLogxK
M3 - Article
VL - 103
SP - 545
EP - 547
JO - Annals of Internal Medicine
JF - Annals of Internal Medicine
SN - 0003-4819
IS - 4
ER -