Abstract
Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2035-2038 |
| Number of pages | 4 |
| Journal | World Journal of Gastroenterology |
| Volume | 11 |
| Issue number | 13 |
| State | Published - Apr 7 2005 |
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Keywords
- Acute mesenteric
- Portal vein thrombosis
ASJC Scopus subject areas
- Gastroenterology
Cite this
Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis : A case report. / Guglielmi, Alfredo; Fior, Francesca; Halmos, Orsolya; Veraldi, Gian Franco; Rossaro, Lorenzo; Ruzzenente, Andrea; Cordiano, Claudio.
In: World Journal of Gastroenterology, Vol. 11, No. 13, 07.04.2005, p. 2035-2038.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis
T2 - A case report
AU - Guglielmi, Alfredo
AU - Fior, Francesca
AU - Halmos, Orsolya
AU - Veraldi, Gian Franco
AU - Rossaro, Lorenzo
AU - Ruzzenente, Andrea
AU - Cordiano, Claudio
PY - 2005/4/7
Y1 - 2005/4/7
N2 - Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.
AB - Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.
KW - Acute mesenteric
KW - Portal vein thrombosis
UR - http://www.scopus.com/inward/record.url?scp=17144363271&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=17144363271&partnerID=8YFLogxK
M3 - Article
C2 - 15801002
AN - SCOPUS:17144363271
VL - 11
SP - 2035
EP - 2038
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
IS - 13
ER -