Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis: A case report

Alfredo Guglielmi, Francesca Fior, Orsolya Halmos, Gian Franco Veraldi, Lorenzo Rossaro, Andrea Ruzzenente, Claudio Cordiano

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.

Original languageEnglish (US)
Pages (from-to)2035-2038
Number of pages4
JournalWorld Journal of Gastroenterology
Volume11
Issue number13
StatePublished - Apr 7 2005

Fingerprint

Mesenteric Veins
Fibrinolysis
Portal Vein
Ulcerative Colitis
Thrombosis
Plasminogen Activators
Thrombolytic Therapy
Portal System
Therapeutics
Thrombectomy
Heparin
Catheters

Keywords

  • Acute mesenteric
  • Portal vein thrombosis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Guglielmi, A., Fior, F., Halmos, O., Veraldi, G. F., Rossaro, L., Ruzzenente, A., & Cordiano, C. (2005). Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis: A case report. World Journal of Gastroenterology, 11(13), 2035-2038.

Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis : A case report. / Guglielmi, Alfredo; Fior, Francesca; Halmos, Orsolya; Veraldi, Gian Franco; Rossaro, Lorenzo; Ruzzenente, Andrea; Cordiano, Claudio.

In: World Journal of Gastroenterology, Vol. 11, No. 13, 07.04.2005, p. 2035-2038.

Research output: Contribution to journalArticle

Guglielmi, A, Fior, F, Halmos, O, Veraldi, GF, Rossaro, L, Ruzzenente, A & Cordiano, C 2005, 'Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis: A case report', World Journal of Gastroenterology, vol. 11, no. 13, pp. 2035-2038.
Guglielmi, Alfredo ; Fior, Francesca ; Halmos, Orsolya ; Veraldi, Gian Franco ; Rossaro, Lorenzo ; Ruzzenente, Andrea ; Cordiano, Claudio. / Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis : A case report. In: World Journal of Gastroenterology. 2005 ; Vol. 11, No. 13. pp. 2035-2038.
@article{1ca6c76a085d48c39ce80f9fb47443e0,
title = "Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis: A case report",
abstract = "Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.",
keywords = "Acute mesenteric, Portal vein thrombosis",
author = "Alfredo Guglielmi and Francesca Fior and Orsolya Halmos and Veraldi, {Gian Franco} and Lorenzo Rossaro and Andrea Ruzzenente and Claudio Cordiano",
year = "2005",
month = "4",
day = "7",
language = "English (US)",
volume = "11",
pages = "2035--2038",
journal = "World Journal of Gastroenterology",
issn = "1007-9327",
publisher = "WJG Press",
number = "13",

}

TY - JOUR

T1 - Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis

T2 - A case report

AU - Guglielmi, Alfredo

AU - Fior, Francesca

AU - Halmos, Orsolya

AU - Veraldi, Gian Franco

AU - Rossaro, Lorenzo

AU - Ruzzenente, Andrea

AU - Cordiano, Claudio

PY - 2005/4/7

Y1 - 2005/4/7

N2 - Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.

AB - Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.

KW - Acute mesenteric

KW - Portal vein thrombosis

UR - http://www.scopus.com/inward/record.url?scp=17144363271&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=17144363271&partnerID=8YFLogxK

M3 - Article

C2 - 15801002

AN - SCOPUS:17144363271

VL - 11

SP - 2035

EP - 2038

JO - World Journal of Gastroenterology

JF - World Journal of Gastroenterology

SN - 1007-9327

IS - 13

ER -