TY - JOUR
T1 - Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis
T2 - A case report
AU - Guglielmi, Alfredo
AU - Fior, Francesca
AU - Halmos, Orsolya
AU - Veraldi, Gian Franco
AU - Rossaro, Lorenzo
AU - Ruzzenente, Andrea
AU - Cordiano, Claudio
PY - 2005/4/7
Y1 - 2005/4/7
N2 - Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.
AB - Aim: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection. Methods: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter. Results: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved. Conclusion: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis.
KW - Acute mesenteric
KW - Portal vein thrombosis
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M3 - Article
C2 - 15801002
AN - SCOPUS:17144363271
VL - 11
SP - 2035
EP - 2038
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
IS - 13
ER -