Transcutaneous carbon dioxide for short-term monitoring of neonates

Gerald J Kost, J. L. Chow, M. A. Kenny

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We studied transcutaneous P(CO)2 monitoring in 70 neonates, most of them premature with respiratory distress syndrome. Measurements were at 44°C. Calibration drift was large in some instances. Least squares linear regression analyses of transcutaneous P(CO)2 (y) vs arterial P(CO)2 (x) in kilopascals showed, for all observations (n = 516), for one observation randomly selected from each patient (n = 70), and for the first observation from each patient (n = 70): y = -0.28 + 1.80x, y = 0.01 + 1.74x, and y = 0.73 + 1.63x, respectively. Regression lines for individual patients with 14 or more observations each were not coincident (F = 2.80, p < 0.002). Transcutaneous P(CO)2 monitoring was most useful clinically as a means of following short-term trends in arterial P(CO)2 continuously during extubation and afterwards when avoiding re-intubation. In view of the potential for error associated with drift, we recommend that intervals between calibrations be limited to about 3 h.

Original languageEnglish (US)
Pages (from-to)1534-1536
Number of pages3
JournalClinical Chemistry
Volume29
Issue number8
StatePublished - 1983
Externally publishedYes

Fingerprint

Carbon Monoxide
Carbon Dioxide
Newborn Infant
Monitoring
Calibration
Observation
Least-Squares Analysis
Intubation
Linear regression
Linear Models
Regression Analysis

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Transcutaneous carbon dioxide for short-term monitoring of neonates. / Kost, Gerald J; Chow, J. L.; Kenny, M. A.

In: Clinical Chemistry, Vol. 29, No. 8, 1983, p. 1534-1536.

Research output: Contribution to journalArticle

Kost, GJ, Chow, JL & Kenny, MA 1983, 'Transcutaneous carbon dioxide for short-term monitoring of neonates', Clinical Chemistry, vol. 29, no. 8, pp. 1534-1536.
Kost, Gerald J ; Chow, J. L. ; Kenny, M. A. / Transcutaneous carbon dioxide for short-term monitoring of neonates. In: Clinical Chemistry. 1983 ; Vol. 29, No. 8. pp. 1534-1536.
@article{5441c4fe02e94e6cb9d97b03b3a7ecf8,
title = "Transcutaneous carbon dioxide for short-term monitoring of neonates",
abstract = "We studied transcutaneous P(CO)2 monitoring in 70 neonates, most of them premature with respiratory distress syndrome. Measurements were at 44°C. Calibration drift was large in some instances. Least squares linear regression analyses of transcutaneous P(CO)2 (y) vs arterial P(CO)2 (x) in kilopascals showed, for all observations (n = 516), for one observation randomly selected from each patient (n = 70), and for the first observation from each patient (n = 70): y = -0.28 + 1.80x, y = 0.01 + 1.74x, and y = 0.73 + 1.63x, respectively. Regression lines for individual patients with 14 or more observations each were not coincident (F = 2.80, p < 0.002). Transcutaneous P(CO)2 monitoring was most useful clinically as a means of following short-term trends in arterial P(CO)2 continuously during extubation and afterwards when avoiding re-intubation. In view of the potential for error associated with drift, we recommend that intervals between calibrations be limited to about 3 h.",
author = "Kost, {Gerald J} and Chow, {J. L.} and Kenny, {M. A.}",
year = "1983",
language = "English (US)",
volume = "29",
pages = "1534--1536",
journal = "Clinical Chemistry",
issn = "0009-9147",
publisher = "American Association for Clinical Chemistry Inc.",
number = "8",

}

TY - JOUR

T1 - Transcutaneous carbon dioxide for short-term monitoring of neonates

AU - Kost, Gerald J

AU - Chow, J. L.

AU - Kenny, M. A.

PY - 1983

Y1 - 1983

N2 - We studied transcutaneous P(CO)2 monitoring in 70 neonates, most of them premature with respiratory distress syndrome. Measurements were at 44°C. Calibration drift was large in some instances. Least squares linear regression analyses of transcutaneous P(CO)2 (y) vs arterial P(CO)2 (x) in kilopascals showed, for all observations (n = 516), for one observation randomly selected from each patient (n = 70), and for the first observation from each patient (n = 70): y = -0.28 + 1.80x, y = 0.01 + 1.74x, and y = 0.73 + 1.63x, respectively. Regression lines for individual patients with 14 or more observations each were not coincident (F = 2.80, p < 0.002). Transcutaneous P(CO)2 monitoring was most useful clinically as a means of following short-term trends in arterial P(CO)2 continuously during extubation and afterwards when avoiding re-intubation. In view of the potential for error associated with drift, we recommend that intervals between calibrations be limited to about 3 h.

AB - We studied transcutaneous P(CO)2 monitoring in 70 neonates, most of them premature with respiratory distress syndrome. Measurements were at 44°C. Calibration drift was large in some instances. Least squares linear regression analyses of transcutaneous P(CO)2 (y) vs arterial P(CO)2 (x) in kilopascals showed, for all observations (n = 516), for one observation randomly selected from each patient (n = 70), and for the first observation from each patient (n = 70): y = -0.28 + 1.80x, y = 0.01 + 1.74x, and y = 0.73 + 1.63x, respectively. Regression lines for individual patients with 14 or more observations each were not coincident (F = 2.80, p < 0.002). Transcutaneous P(CO)2 monitoring was most useful clinically as a means of following short-term trends in arterial P(CO)2 continuously during extubation and afterwards when avoiding re-intubation. In view of the potential for error associated with drift, we recommend that intervals between calibrations be limited to about 3 h.

UR - http://www.scopus.com/inward/record.url?scp=0020616971&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020616971&partnerID=8YFLogxK

M3 - Article

VL - 29

SP - 1534

EP - 1536

JO - Clinical Chemistry

JF - Clinical Chemistry

SN - 0009-9147

IS - 8

ER -