We studied transcutaneous P(CO)2 monitoring in 70 neonates, most of them premature with respiratory distress syndrome. Measurements were at 44°C. Calibration drift was large in some instances. Least squares linear regression analyses of transcutaneous P(CO)2 (y) vs arterial P(CO)2 (x) in kilopascals showed, for all observations (n = 516), for one observation randomly selected from each patient (n = 70), and for the first observation from each patient (n = 70): y = -0.28 + 1.80x, y = 0.01 + 1.74x, and y = 0.73 + 1.63x, respectively. Regression lines for individual patients with 14 or more observations each were not coincident (F = 2.80, p < 0.002). Transcutaneous P(CO)2 monitoring was most useful clinically as a means of following short-term trends in arterial P(CO)2 continuously during extubation and afterwards when avoiding re-intubation. In view of the potential for error associated with drift, we recommend that intervals between calibrations be limited to about 3 h.
|Original language||English (US)|
|Number of pages||3|
|State||Published - 1983|
ASJC Scopus subject areas
- Clinical Biochemistry