Transcutaneous carbon dioxide for short-term monitoring of neonates

Gerald J Kost, J. L. Chow, M. A. Kenny

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Abstract

We studied transcutaneous P(CO)2 monitoring in 70 neonates, most of them premature with respiratory distress syndrome. Measurements were at 44°C. Calibration drift was large in some instances. Least squares linear regression analyses of transcutaneous P(CO)2 (y) vs arterial P(CO)2 (x) in kilopascals showed, for all observations (n = 516), for one observation randomly selected from each patient (n = 70), and for the first observation from each patient (n = 70): y = -0.28 + 1.80x, y = 0.01 + 1.74x, and y = 0.73 + 1.63x, respectively. Regression lines for individual patients with 14 or more observations each were not coincident (F = 2.80, p < 0.002). Transcutaneous P(CO)2 monitoring was most useful clinically as a means of following short-term trends in arterial P(CO)2 continuously during extubation and afterwards when avoiding re-intubation. In view of the potential for error associated with drift, we recommend that intervals between calibrations be limited to about 3 h.

Original languageEnglish (US)
Pages (from-to)1534-1536
Number of pages3
JournalClinical Chemistry
Volume29
Issue number8
StatePublished - 1983
Externally publishedYes

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ASJC Scopus subject areas

  • Clinical Biochemistry

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