Trajectory of development in adolescents and adults with autism

Marsha Mailick Seltzer, Paul Shattuck, Leonard J Abbeduto, Jan S. Greenberg

Research output: Contribution to journalArticlepeer-review

337 Scopus citations


This article seeks to elucidate the trajectory of development in adolescents and adults with autism. Prospective, retrospective, and cross-sectional studies are reviewed to reveal the manifestation of and changes in the core symptoms of autism in adolescence and adulthood. Comparing children with adolescents and adults, modest degrees of symptom abatement and improvement in skills have been documented in multiple studies, as are increases in verbal and decreases in performance IQ. Nevertheless, most individuals do not attain normative outcomes in adulthood and continue to manifest significant degrees of symptomatology and dependency. However, a small sub-group (about 15%) has more favorable adult outcomes.

Original languageEnglish (US)
Pages (from-to)234-247
Number of pages14
JournalMental Retardation and Developmental Disabilities Research Reviews
Issue number4
StatePublished - 2004
Externally publishedYes


  • Adolescence
  • Autism
  • Life course development

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Genetics(clinical)


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