Trajectories and profiles of adaptive behavior in males with fragile X syndrome: Multicenter studies

Elisabeth Dykens, Sharon Ort, Ira Cohen, Brenda Finucane, Gail Spiridigliozzi, Ave Lachiewicz, Allan Reiss, Lisa Freund, Randi J Hagerman, Rebecca O'Connor

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

We conducted two multicenter studies on adaptive trajectories and profiles in males with fragile X syndrome. Study 1 longitudinally assessed 29 males ages 1-20 years using age-equivalent scores from the Vineland Adaptive Behavior Scales. Fragile X boys ages 1-10 years showed significant gains in adaptive skills from first to second testing; males ages 11-20 years were stable in their adaptive development. Study 2 cross-sectionally examined 132 males ages 1-20 years. Significant age-related gains were found in boys ages 1-10, particularly in preschool children. Subjects ages 11-20 showed increased variability and nonsignificant relations between age and adaptive skills. Preliminary findings from 26 young adults with fragile X syndrome ages 21-40 years showed stable age-equivalent adaptive scores during these years. Relative strengths in daily living skills and weaknesses in communication were only evident among older subjects. Significant relations were found between adaptive behavior standard scores and IQ; these two scores also showed age-related declines that likely parallel one another. Findings are related to adaptive features in other genetic syndromes, and to directions for future adaptive behavior research.

Original languageEnglish (US)
Pages (from-to)287-301
Number of pages15
JournalJournal of Autism and Developmental Disorders
Volume26
Issue number3
DOIs
StatePublished - 1996
Externally publishedYes

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Fragile X Syndrome
Psychological Adaptation
Multicenter Studies
Preschool Children
Young Adult
Communication
Research

ASJC Scopus subject areas

  • Psychology(all)
  • Developmental and Educational Psychology

Cite this

Dykens, E., Ort, S., Cohen, I., Finucane, B., Spiridigliozzi, G., Lachiewicz, A., ... O'Connor, R. (1996). Trajectories and profiles of adaptive behavior in males with fragile X syndrome: Multicenter studies. Journal of Autism and Developmental Disorders, 26(3), 287-301. https://doi.org/10.1007/BF02172475

Trajectories and profiles of adaptive behavior in males with fragile X syndrome : Multicenter studies. / Dykens, Elisabeth; Ort, Sharon; Cohen, Ira; Finucane, Brenda; Spiridigliozzi, Gail; Lachiewicz, Ave; Reiss, Allan; Freund, Lisa; Hagerman, Randi J; O'Connor, Rebecca.

In: Journal of Autism and Developmental Disorders, Vol. 26, No. 3, 1996, p. 287-301.

Research output: Contribution to journalArticle

Dykens, E, Ort, S, Cohen, I, Finucane, B, Spiridigliozzi, G, Lachiewicz, A, Reiss, A, Freund, L, Hagerman, RJ & O'Connor, R 1996, 'Trajectories and profiles of adaptive behavior in males with fragile X syndrome: Multicenter studies', Journal of Autism and Developmental Disorders, vol. 26, no. 3, pp. 287-301. https://doi.org/10.1007/BF02172475
Dykens, Elisabeth ; Ort, Sharon ; Cohen, Ira ; Finucane, Brenda ; Spiridigliozzi, Gail ; Lachiewicz, Ave ; Reiss, Allan ; Freund, Lisa ; Hagerman, Randi J ; O'Connor, Rebecca. / Trajectories and profiles of adaptive behavior in males with fragile X syndrome : Multicenter studies. In: Journal of Autism and Developmental Disorders. 1996 ; Vol. 26, No. 3. pp. 287-301.
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