Tracheobronchial amyloidosis in a patient with Sjogren syndrome

Hanine Inaty, Erik Folch, Christopher Stephen, Adnan Majid

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Summary: Pulmonary amyloidosis in the setting of Sjogren syndrome is rare. It most commonly presents in form of multinodular disease with or without cysts formation. Amyloid plaques may also deposit in the airway submucosa, causing airway narrowing; the condition referred as "tracheobronchial amyloidosis" (TBA). Patients with this condition most commonly present with postobstructive pneumonia, wheezing, and occasionally hemoptysis. Endoscopic therapies, using flexible forceps with or without laser therapy is crucial to alleviate the obstruction and control the bleeding. Other therapeutic modalities such as external beam radiation has been shown to be promising; however, further data are still needed. To our knowledge, our patient is the first reported case of TBA in a setting of Sjogren syndrome.

Original languageEnglish (US)
Pages (from-to)261-265
Number of pages5
JournalJournal of Bronchology and Interventional Pulmonology
Issue number3
StatePublished - Jul 2013
Externally publishedYes


  • Bronchoscopy
  • Laser therapy
  • Mechanical debridement
  • Pulmonary amyloidosis
  • Sjogren syndrome
  • Tracheobronchial amyloidosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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