Abstract
This chapter focuses on six elements-cobalt (Co), copper (Cu), manganese (Mn), molybdenum (Mo), selenium (Se), and zinc (Zn)-to illustrate the concepts important to trace element metabolism and disease. These elements are chosen because there is evidence that perturbations in their metabolism are relatively common. Other biologically active trace elements, although potentially important, often require special conditions or long periods of deprivation before signs of deficiency are recognized. Metal ions in combination with numerous organic accessory and catalytic factors (e.g., various vitamins) play important roles in enhancing specificity and providing additional properties that allow complementary forces, and arrangements to improve the orientation and efficiency of catalysis. In enzyme transition states, metals influence the entropic components of enzymatic reactions. Metals allow the formation of metastable bonds and play roles in entasis. Some minerals are important in organizing water structure, while others act as Lewis acids and bases. Appropriate intake levels of certain chemical elements are required to maintain optimal health.
| Original language | English (US) |
|---|---|
| Title of host publication | Clinical Biochemistry of Domestic Animals |
| Publisher | Elsevier Inc. |
| Pages | 663-693 |
| Number of pages | 31 |
| ISBN (Print) | 9780123704917 |
| DOIs | |
| State | Published - 2008 |
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ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
Cite this
Trace Minerals. / Rucker, Robert B.; Fascetti, Andrea J; Keen, Carl L.
Clinical Biochemistry of Domestic Animals. Elsevier Inc., 2008. p. 663-693.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Trace Minerals
AU - Rucker, Robert B.
AU - Fascetti, Andrea J
AU - Keen, Carl L
PY - 2008
Y1 - 2008
N2 - This chapter focuses on six elements-cobalt (Co), copper (Cu), manganese (Mn), molybdenum (Mo), selenium (Se), and zinc (Zn)-to illustrate the concepts important to trace element metabolism and disease. These elements are chosen because there is evidence that perturbations in their metabolism are relatively common. Other biologically active trace elements, although potentially important, often require special conditions or long periods of deprivation before signs of deficiency are recognized. Metal ions in combination with numerous organic accessory and catalytic factors (e.g., various vitamins) play important roles in enhancing specificity and providing additional properties that allow complementary forces, and arrangements to improve the orientation and efficiency of catalysis. In enzyme transition states, metals influence the entropic components of enzymatic reactions. Metals allow the formation of metastable bonds and play roles in entasis. Some minerals are important in organizing water structure, while others act as Lewis acids and bases. Appropriate intake levels of certain chemical elements are required to maintain optimal health.
AB - This chapter focuses on six elements-cobalt (Co), copper (Cu), manganese (Mn), molybdenum (Mo), selenium (Se), and zinc (Zn)-to illustrate the concepts important to trace element metabolism and disease. These elements are chosen because there is evidence that perturbations in their metabolism are relatively common. Other biologically active trace elements, although potentially important, often require special conditions or long periods of deprivation before signs of deficiency are recognized. Metal ions in combination with numerous organic accessory and catalytic factors (e.g., various vitamins) play important roles in enhancing specificity and providing additional properties that allow complementary forces, and arrangements to improve the orientation and efficiency of catalysis. In enzyme transition states, metals influence the entropic components of enzymatic reactions. Metals allow the formation of metastable bonds and play roles in entasis. Some minerals are important in organizing water structure, while others act as Lewis acids and bases. Appropriate intake levels of certain chemical elements are required to maintain optimal health.
UR - http://www.scopus.com/inward/record.url?scp=84866853975&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84866853975&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-370491-7.00022-2
DO - 10.1016/B978-0-12-370491-7.00022-2
M3 - Chapter
AN - SCOPUS:84866853975
SN - 9780123704917
SP - 663
EP - 693
BT - Clinical Biochemistry of Domestic Animals
PB - Elsevier Inc.
ER -