Abstract
Dietary deficiency of trace metals among human populations, once thought to be exceedingly rare, has recently gained attention as a potential public health problem. The consumption of highly refined and heavily processed foods reduces the trace element content of the diet. The higher trace element requirements during pregnancy, lactation, growth, development, and chronic disease may further contribute to states of marginal trace metal nutriture. Experimental animal studies have demonstrated that even marginal trace element deprivation during critical periods of growth and development or, alternatively, during prolonged deficiency in adults can significantly alter immunologic function Furthermore, trace metal nutriture has been shown to affect the initiation and progression of a large variety of neoplasia. These observations are of major significance to the aged and suggest the need to vigorously define the trace metal status and its relationship to immunity in this nutritionally at-risk population.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 374-378 |
| Number of pages | 5 |
| Journal | Journal of the American Geriatrics Society |
| Volume | 31 |
| Issue number | 6 |
| State | Published - 1983 |
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ASJC Scopus subject areas
- Geriatrics and Gerontology
Cite this
Trace metals, aging, and immunity. / Gershwin, M. Eric; Beach, R.; Hurley, L.
In: Journal of the American Geriatrics Society, Vol. 31, No. 6, 1983, p. 374-378.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Trace metals, aging, and immunity
AU - Gershwin, M. Eric
AU - Beach, R.
AU - Hurley, L.
PY - 1983
Y1 - 1983
N2 - Dietary deficiency of trace metals among human populations, once thought to be exceedingly rare, has recently gained attention as a potential public health problem. The consumption of highly refined and heavily processed foods reduces the trace element content of the diet. The higher trace element requirements during pregnancy, lactation, growth, development, and chronic disease may further contribute to states of marginal trace metal nutriture. Experimental animal studies have demonstrated that even marginal trace element deprivation during critical periods of growth and development or, alternatively, during prolonged deficiency in adults can significantly alter immunologic function Furthermore, trace metal nutriture has been shown to affect the initiation and progression of a large variety of neoplasia. These observations are of major significance to the aged and suggest the need to vigorously define the trace metal status and its relationship to immunity in this nutritionally at-risk population.
AB - Dietary deficiency of trace metals among human populations, once thought to be exceedingly rare, has recently gained attention as a potential public health problem. The consumption of highly refined and heavily processed foods reduces the trace element content of the diet. The higher trace element requirements during pregnancy, lactation, growth, development, and chronic disease may further contribute to states of marginal trace metal nutriture. Experimental animal studies have demonstrated that even marginal trace element deprivation during critical periods of growth and development or, alternatively, during prolonged deficiency in adults can significantly alter immunologic function Furthermore, trace metal nutriture has been shown to affect the initiation and progression of a large variety of neoplasia. These observations are of major significance to the aged and suggest the need to vigorously define the trace metal status and its relationship to immunity in this nutritionally at-risk population.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020957257&partnerID=8YFLogxK
M3 - Article
C2 - 6343468
AN - SCOPUS:0020957257
VL - 31
SP - 374
EP - 378
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
SN - 0002-8614
IS - 6
ER -