Trabecular shear stress in human vertebral cancellous bone: Intra- and inter-individual variations

Yener N. Yeni, Fu J. Hou, Deepak Vashishth, David P Fyhrie

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Correlation of the mean and standard deviation of trabecular stresses has been proposed as a mechanism by which a strong relationship between the apparent strength and stiffness of cancellous bone can be achieved. The current study examined whether the relationship between the mean and standard deviation of trabecular von Mises stresses can be generalized for any group of cancellous bone. Cylindrical human vertebral cancellous bone specimens were cut in the infero-superior direction from T12 of 23 individuals (inter-individual group). Thirty nine additional specimens were prepared similarly from the T4-T12 and L2-L5 vertebrae of a 63 year old male (intra-individual group). The specimens were scanned by micro-computed tomography (μCT) and trabecular von Mises stresses were calculated using finite element modeling. The expected value, standard deviation and coefficient of variation of the von Mises stress were calculated form a three-parameter Weibull function fitted to von Mises stress data from each specimen. It was found that the average and standard deviation of trabecular von Mises shear stress were: (i) correlated with each other, supporting the idea that high correlation between the apparent strength and stiffness of cancellous bone can be achieved through controlling the trabecular level shear stress variations, (ii) dependent on anatomical site and sample group, suggesting that the variation of stresses are correlated to the mean stress to different degrees between vertebrae and individuals, and (iii) dependent on bone volume fraction, consistent with the idea that shear stress is less well controlled in bones with low BV/TV. The conversion of infero-superior loading into trabecular von Mises stresses was maximum for the tissue at the junction of the thoracic and lumbar spine (T12-L1) consistent with this junction being a common site of vertebral fracture.

Original languageEnglish (US)
Pages (from-to)1341-1346
Number of pages6
JournalJournal of Biomechanics
Volume34
Issue number10
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Shear stress
Bone
Spine
Bone and Bones
Thorax
Tomography
Stiffness
Cancellous Bone
Volume fraction
Tissue

Keywords

  • Cancellous bone
  • Finite element analysis
  • Micro tomography
  • Stress
  • Vertebra

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Trabecular shear stress in human vertebral cancellous bone : Intra- and inter-individual variations. / Yeni, Yener N.; Hou, Fu J.; Vashishth, Deepak; Fyhrie, David P.

In: Journal of Biomechanics, Vol. 34, No. 10, 2001, p. 1341-1346.

Research output: Contribution to journalArticle

Yeni, Yener N. ; Hou, Fu J. ; Vashishth, Deepak ; Fyhrie, David P. / Trabecular shear stress in human vertebral cancellous bone : Intra- and inter-individual variations. In: Journal of Biomechanics. 2001 ; Vol. 34, No. 10. pp. 1341-1346.
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