TY - JOUR
T1 - Towards a Neurodevelopmental Model of Clinical Case Formulation
AU - Friedman, Marjorie Solomon
AU - Hessl, David R
AU - Chiu, Sufen
AU - Olsen, Emily
AU - Hendren, Robert L.
PY - 2009/3
Y1 - 2009/3
N2 - Rapid advances in molecular genetics and neuroimaging over the last 10 to 20 years have been a catalyst for research in neurobiology, developmental psychopathology, and translational neuroscience. Methods of study in psychiatry, previously described as "slow maturing," now are becoming sufficiently sophisticated to more effectively investigate the biology of higher mental processes. Despite these technologic advances, the recognition that psychiatric disorders are disorders of neurodevelopment, and the importance of case formulation to clinical practice, a neurodevelopmental model of case formulation has not yet been articulated. The goals of this article, which is organized as a clinical case conference, are to begin to articulate a neurodevelopmental model of case formulation, to illustrate its value, and finally to explore how clinical psychiatric practice might evolve in the future if this model were employed.
AB - Rapid advances in molecular genetics and neuroimaging over the last 10 to 20 years have been a catalyst for research in neurobiology, developmental psychopathology, and translational neuroscience. Methods of study in psychiatry, previously described as "slow maturing," now are becoming sufficiently sophisticated to more effectively investigate the biology of higher mental processes. Despite these technologic advances, the recognition that psychiatric disorders are disorders of neurodevelopment, and the importance of case formulation to clinical practice, a neurodevelopmental model of case formulation has not yet been articulated. The goals of this article, which is organized as a clinical case conference, are to begin to articulate a neurodevelopmental model of case formulation, to illustrate its value, and finally to explore how clinical psychiatric practice might evolve in the future if this model were employed.
KW - Case formulation
KW - Endophenotypes
KW - Fragile X Syndrome
KW - Neurodevelopment
KW - Pervasive developmental disorder
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U2 - 10.1016/j.psc.2008.11.003
DO - 10.1016/j.psc.2008.11.003
M3 - Article
C2 - 19248925
AN - SCOPUS:60549106679
VL - 32
SP - 199
EP - 211
JO - Psychiatric Clinics of North America
JF - Psychiatric Clinics of North America
SN - 0193-953X
IS - 1
ER -