Toward the etiologies of congenital heart diseases

Andrew N Pelech; Ulrich Broeckel

doi:10.1016/j.clp.2005.09.005

Toward the etiologies of congenital heart diseases

Andrew N Pelech, Ulrich Broeckel

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

Congenital heart disease remains a significant cause of morbidity and mortality. In recent years, significant advances in molecular genetics, improved understanding of morphogenesis, recognition of specific patterning of abnormalities within and between species, and the impact of the Human Genome Project have accounted for these advances. Continued rapid developments in genomics and proteomics are anticipated. Epidemiologic investigations continue to be necessary to assess the influence of the environment on genetics. It is exciting to know that we are on the threshold of influencing the occurrence of congenital heart diseases.

Original language	English (US)
Pages (from-to)	825-844
Number of pages	20
Journal	Clinics in Perinatology
Volume	32
Issue number	4
DOIs	https://doi.org/10.1016/j.clp.2005.09.005
State	Published - Dec 2005
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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author = "Pelech, {Andrew N} and Ulrich Broeckel",

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AU - Broeckel, Ulrich

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AB - Congenital heart disease remains a significant cause of morbidity and mortality. In recent years, significant advances in molecular genetics, improved understanding of morphogenesis, recognition of specific patterning of abnormalities within and between species, and the impact of the Human Genome Project have accounted for these advances. Continued rapid developments in genomics and proteomics are anticipated. Epidemiologic investigations continue to be necessary to assess the influence of the environment on genetics. It is exciting to know that we are on the threshold of influencing the occurrence of congenital heart diseases.

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Toward the etiologies of congenital heart diseases

Abstract

ASJC Scopus subject areas

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