Toward a new method of analyzing cardiac performance

Crystal M Ripplinger, D. L. Ewert, S. C. Koenig

Research output: Contribution to journalArticle

Abstract

Aside from the traditional diagnostic tools used to assess cardiac performance, such as blood pressure and cardiac output, cardiac source parameters can also be used as an indication of overall cardiac health. The cardiac source parameters under investigation are myocardial visco-elastic properties. The objective of this study is to model the left ventricle using electrical circuits, then use these models to estimate the cardiac source parameters. Two electrical models of the left ventricle have been developed, using a resistor (R) to model viscous losses, a capacitor (C) to represent inverse elastance, and a time-varying pressure source, which models the left ventricular pressure during an isovolumic beat. One model uses a single resistor and the other uses the two elements (R and C) in parallel. The differential equations describing these models have been derived, and a minimization procedure was used to adjust values of R and C in the differential equations until a good agreement between experimental and calculated left ventricular pressure was reached. Preliminary results indicate that the model including a parallel combination of R and C provides a better fit between experimental and calculated pressures. It is hoped that these parameters may one day provide clinicians with yet another diagnostic tool to help discover the source of cardiac disorders.

Original languageEnglish (US)
Pages (from-to)313-318
Number of pages6
JournalBiomedical Sciences Instrumentation
Volume37
StatePublished - 2001
Externally publishedYes

Fingerprint

Ventricular Pressure
Heart Ventricles
Pressure
Cardiac Output
Blood Pressure
Health
Resistors
Differential equations
Blood pressure
Capacitors
Networks (circuits)

Keywords

  • Cardiac models
  • Source
  • Viscoelastic properties

ASJC Scopus subject areas

  • Hardware and Architecture

Cite this

Toward a new method of analyzing cardiac performance. / Ripplinger, Crystal M; Ewert, D. L.; Koenig, S. C.

In: Biomedical Sciences Instrumentation, Vol. 37, 2001, p. 313-318.

Research output: Contribution to journalArticle

@article{45f5a3bef4ed4b15911f5ece628e3f08,
title = "Toward a new method of analyzing cardiac performance",
abstract = "Aside from the traditional diagnostic tools used to assess cardiac performance, such as blood pressure and cardiac output, cardiac source parameters can also be used as an indication of overall cardiac health. The cardiac source parameters under investigation are myocardial visco-elastic properties. The objective of this study is to model the left ventricle using electrical circuits, then use these models to estimate the cardiac source parameters. Two electrical models of the left ventricle have been developed, using a resistor (R) to model viscous losses, a capacitor (C) to represent inverse elastance, and a time-varying pressure source, which models the left ventricular pressure during an isovolumic beat. One model uses a single resistor and the other uses the two elements (R and C) in parallel. The differential equations describing these models have been derived, and a minimization procedure was used to adjust values of R and C in the differential equations until a good agreement between experimental and calculated left ventricular pressure was reached. Preliminary results indicate that the model including a parallel combination of R and C provides a better fit between experimental and calculated pressures. It is hoped that these parameters may one day provide clinicians with yet another diagnostic tool to help discover the source of cardiac disorders.",
keywords = "Cardiac models, Source, Viscoelastic properties",
author = "Ripplinger, {Crystal M} and Ewert, {D. L.} and Koenig, {S. C.}",
year = "2001",
language = "English (US)",
volume = "37",
pages = "313--318",
journal = "Biomedical Sciences Instrumentation",
issn = "0067-8856",
publisher = "ISA - Instrumentation, Systems, and Automation Society",

}

TY - JOUR

T1 - Toward a new method of analyzing cardiac performance

AU - Ripplinger, Crystal M

AU - Ewert, D. L.

AU - Koenig, S. C.

PY - 2001

Y1 - 2001

N2 - Aside from the traditional diagnostic tools used to assess cardiac performance, such as blood pressure and cardiac output, cardiac source parameters can also be used as an indication of overall cardiac health. The cardiac source parameters under investigation are myocardial visco-elastic properties. The objective of this study is to model the left ventricle using electrical circuits, then use these models to estimate the cardiac source parameters. Two electrical models of the left ventricle have been developed, using a resistor (R) to model viscous losses, a capacitor (C) to represent inverse elastance, and a time-varying pressure source, which models the left ventricular pressure during an isovolumic beat. One model uses a single resistor and the other uses the two elements (R and C) in parallel. The differential equations describing these models have been derived, and a minimization procedure was used to adjust values of R and C in the differential equations until a good agreement between experimental and calculated left ventricular pressure was reached. Preliminary results indicate that the model including a parallel combination of R and C provides a better fit between experimental and calculated pressures. It is hoped that these parameters may one day provide clinicians with yet another diagnostic tool to help discover the source of cardiac disorders.

AB - Aside from the traditional diagnostic tools used to assess cardiac performance, such as blood pressure and cardiac output, cardiac source parameters can also be used as an indication of overall cardiac health. The cardiac source parameters under investigation are myocardial visco-elastic properties. The objective of this study is to model the left ventricle using electrical circuits, then use these models to estimate the cardiac source parameters. Two electrical models of the left ventricle have been developed, using a resistor (R) to model viscous losses, a capacitor (C) to represent inverse elastance, and a time-varying pressure source, which models the left ventricular pressure during an isovolumic beat. One model uses a single resistor and the other uses the two elements (R and C) in parallel. The differential equations describing these models have been derived, and a minimization procedure was used to adjust values of R and C in the differential equations until a good agreement between experimental and calculated left ventricular pressure was reached. Preliminary results indicate that the model including a parallel combination of R and C provides a better fit between experimental and calculated pressures. It is hoped that these parameters may one day provide clinicians with yet another diagnostic tool to help discover the source of cardiac disorders.

KW - Cardiac models

KW - Source

KW - Viscoelastic properties

UR - http://www.scopus.com/inward/record.url?scp=0035033492&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035033492&partnerID=8YFLogxK

M3 - Article

C2 - 11347409

AN - SCOPUS:0035033492

VL - 37

SP - 313

EP - 318

JO - Biomedical Sciences Instrumentation

JF - Biomedical Sciences Instrumentation

SN - 0067-8856

ER -