Total-Body PET Imaging of Musculoskeletal Disorders

Abhijit J. Chaudhari; William Y. Raynor; Ali Gholamrezanezhad; Thomas J. Werner; Chamith S. Rajapakse; Abass Alavi

doi:10.1016/j.cpet.2020.09.012

Total-Body PET Imaging of Musculoskeletal Disorders

Abhijit J. Chaudhari, William Y. Raynor, Ali Gholamrezanezhad, Thomas J. Werner, Chamith S. Rajapakse, Abass Alavi

Radiology

Research output: Contribution to journal › Review article › peer-review

Abstract

Imaging of musculoskeletal disorders, including arthritis, infection, osteoporosis, sarcopenia, and malignancies, is often limited when using conventional modalities such as radiography, computed tomography (CT), and MR imaging. As a result of recent advances in Positron Emission Tomography (PET) instrumentation, total-body PET/CT offers a longer axial field-of-view, higher geometric sensitivity, and higher spatial resolution compared with standard PET systems. This article discusses the potential applications of total-body PET/CT imaging in the assessment of musculoskeletal disorders.

Original language	English (US)
Pages (from-to)	99-117
Number of pages	19
Journal	PET Clinics
Volume	16
Issue number	1
DOIs	https://doi.org/10.1016/j.cpet.2020.09.012
State	Published - Jan 2021

Keywords

Arthritis
Cancer
Fever of unknown origin
Osteoporosis
Osteosarcoma
PET/CT
PET/MR imaging
Sarcopenia

ASJC Scopus subject areas

Radiation
Radiology Nuclear Medicine and imaging

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title = "Total-Body PET Imaging of Musculoskeletal Disorders",

abstract = "Imaging of musculoskeletal disorders, including arthritis, infection, osteoporosis, sarcopenia, and malignancies, is often limited when using conventional modalities such as radiography, computed tomography (CT), and MR imaging. As a result of recent advances in Positron Emission Tomography (PET) instrumentation, total-body PET/CT offers a longer axial field-of-view, higher geometric sensitivity, and higher spatial resolution compared with standard PET systems. This article discusses the potential applications of total-body PET/CT imaging in the assessment of musculoskeletal disorders.",

keywords = "Arthritis, Cancer, Fever of unknown origin, Osteoporosis, Osteosarcoma, PET/CT, PET/MR imaging, Sarcopenia",

author = "Chaudhari, {Abhijit J.} and Raynor, {William Y.} and Ali Gholamrezanezhad and Werner, {Thomas J.} and Rajapakse, {Chamith S.} and Abass Alavi",

note = "Funding Information: The authors acknowledge support by the National Institutes of Health under award number R01AR076088 . ",

year = "2021",

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doi = "10.1016/j.cpet.2020.09.012",

language = "English (US)",

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AU - Chaudhari, Abhijit J.

AU - Raynor, William Y.

AU - Gholamrezanezhad, Ali

AU - Werner, Thomas J.

AU - Rajapakse, Chamith S.

AU - Alavi, Abass

N1 - Funding Information: The authors acknowledge support by the National Institutes of Health under award number R01AR076088 .

PY - 2021/1

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N2 - Imaging of musculoskeletal disorders, including arthritis, infection, osteoporosis, sarcopenia, and malignancies, is often limited when using conventional modalities such as radiography, computed tomography (CT), and MR imaging. As a result of recent advances in Positron Emission Tomography (PET) instrumentation, total-body PET/CT offers a longer axial field-of-view, higher geometric sensitivity, and higher spatial resolution compared with standard PET systems. This article discusses the potential applications of total-body PET/CT imaging in the assessment of musculoskeletal disorders.

AB - Imaging of musculoskeletal disorders, including arthritis, infection, osteoporosis, sarcopenia, and malignancies, is often limited when using conventional modalities such as radiography, computed tomography (CT), and MR imaging. As a result of recent advances in Positron Emission Tomography (PET) instrumentation, total-body PET/CT offers a longer axial field-of-view, higher geometric sensitivity, and higher spatial resolution compared with standard PET systems. This article discusses the potential applications of total-body PET/CT imaging in the assessment of musculoskeletal disorders.

KW - Arthritis

KW - Cancer

KW - Fever of unknown origin

KW - Osteoporosis

KW - Osteosarcoma

KW - PET/CT

KW - PET/MR imaging

KW - Sarcopenia

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