Total-body PET Imaging: A New Frontier for the Assessment of Metabolic Disease and Obesity

Maria Chondronikola, Souvik Sarkar

Research output: Contribution to journalReview articlepeer-review

Abstract

Obesity and associated metabolic syndrome are a global public health issue. Understanding the pathophysiology of this systemic disease is of critical importance for the development of future therapeutic interventions to improve clinical outcomes. The multiorgan nature of the pathophysiology of obesity presents a unique challenge. Total-body PET imaging, either static or dynamic, provides a vital set of tools to study organ crosstalk. The visualization and quantification of tissue metabolic kinetics with total-body PET in health and disease provides essential information to better understand disease physiology and potentially develop diagnostic and therapeutic modalities.

Original languageEnglish (US)
JournalPET Clinics
DOIs
StateAccepted/In press - 2020

Keywords

  • Adipose tissue
  • Metabolic syndrome
  • Nonalcoholic fatty liver disease
  • PET
  • Skeletal muscle

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging

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