Topography of the chromatic pattern-onset VEP

Christina Gerth, Peter B. Delahunt, Michael A. Crognale, John S Werner

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The chromatic pattern-onset VEP has been used successfully as a sensitive and objective technique to determine congenital and acquired color vision deficiency. It also has been applied to characterize development, maturation and aging of the chromatic visual pathways. Here we determine the topographic components of the full-field VEP using the multifocal technique. Recordings were made with the VERISTM system that extracts topographic VEPs using a pseudorandom stimulus sequence. Chromatic pattern stimuli were presented in an onset-offset temporal sequence, with colors modulated along different axes in the MBDKL color space. Additional experiments were conducted to verify the S-cone axis for each observer and that our chromatic stimuli were close to isoluminant at different field locations. Our data show reliable and robust chromatic onset VEP responses for multiple retinal areas that conform to pattern-onset full-field VEP waveform characteristics. For stimuli with chromatic contributions, pattern-onsets produced reliable and consistent waveforms whereas for stimuli with large luminance contributions pattern-reversal stimuli were superior. Our method for recording chromatic multifocal pattern-onset VEPs holds promise for clinical application to detect and monitor early retinal and optic nerve changes related to aging and disease.

Original languageEnglish (US)
Pages (from-to)171-182
Number of pages12
JournalJournal of Vision
Volume3
Issue number2
DOIs
StatePublished - Apr 3 2003

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Color
Color Vision Defects
Visual Pathways
Optic Nerve

Keywords

  • Chromatic axes
  • Color
  • Multifocal
  • VEP

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Topography of the chromatic pattern-onset VEP. / Gerth, Christina; Delahunt, Peter B.; Crognale, Michael A.; Werner, John S.

In: Journal of Vision, Vol. 3, No. 2, 03.04.2003, p. 171-182.

Research output: Contribution to journalArticle

Gerth, C, Delahunt, PB, Crognale, MA & Werner, JS 2003, 'Topography of the chromatic pattern-onset VEP', Journal of Vision, vol. 3, no. 2, pp. 171-182. https://doi.org/10.1167/3.2.5
Gerth, Christina ; Delahunt, Peter B. ; Crognale, Michael A. ; Werner, John S. / Topography of the chromatic pattern-onset VEP. In: Journal of Vision. 2003 ; Vol. 3, No. 2. pp. 171-182.
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